undec-2-ynoic acid

Base Information

• Chemical Name: undec-2-ynoic acid
• CAS No.: 54299-08-0
• Molecular Formula: C11H18 O2
• Molecular Weight: 182.263
• Mol file: 54299-08-0.mol

Synonyms:

Chemical Property of undec-2-ynoic acid

Chemical Property:

• Vapor Pressure: 0.000202mmHg at 25°C
• Boiling Point: 304.4°C at 760 mmHg
• Flash Point: 152.1°C
• Density: 0.969g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of undec-2-ynoic acid

There total 7 articles about undec-2-ynoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1-decyne (764-93-2) + carbon dioxide (124-38-9,18923-20-1) → 2-Undecynoic acid (54299-08-0)

Guidance literature:

1-decyne; carbon dioxide; With caesium carbonate; silver(I) iodide; In N,N-dimethyl-formamide; at 50 ℃; for 12h; under 1500.15 Torr; Autoclave;

With hydrogenchloride; In water; Cooling;

DOI:10.1021/ol200638z

Reference yield: 86.5%

ethyl undec-2-ynoate (10519-17-2) → 2-Undecynoic acid (54299-08-0)

Guidance literature:

With lithium hydroxide; In methanol; for 12h; Ambient temperature;

DOI:10.7164/antibiotics.48.1467

Reference yield:

1-methoxy-2-undecynyl phenyl sulfide → 2-Undecynoic acid (54299-08-0)

Guidance literature:

With jones reagent; In acetone; at 20 ℃; for 24h;

DOI:10.1080/00397919708005006

upstream raw materials:

1-decyne

carbon dioxide

ethyl undec-2-ynoate

Undec-2-ynylsulfanyl-benzene

Downstream raw materials:

ethyl undec-2-ynoate

Decan-2-one

Refernces

• 1、 Zhang, Xiao,Zhang, Wen-Zhen,Ren, Xiang,Zhang, Lin-Lin,Lu, Xiao-Bing. "Ligand-free Ag(I)-catalyzed carboxylation of terminal alkynes with CO 2". supporting information; experimental part. p. 2402 - 2405. Retrieved 2011/06/25.
• 2、 Sakai,Kawai,Kamishohara,Odagawa,Suzuki,Uchida,Kawasaki,Tsuruo,Otake. "Structure-antitumor activity relationship of semi-synthetic spicamycin derivatives". . p. 1467 - 1480. Retrieved 2007/10/03.