2H-Pyrazolo(4,3-c)quinoline-2-ethanol, 4,6-dihydro-5-((4-methylphenyl)sulfonyl)-

Base Information

Chemical Name:2H-Pyrazolo(4,3-c)quinoline-2-ethanol, 4,6-dihydro-5-((4-methylphenyl)sulfonyl)-
CAS No.:103688-00-2
Molecular Formula:C₁₉H₁₉N₃O₃S
Molecular Weight:369.444
Hs Code.:
DSSTox Substance ID:DTXSID50146003
Wikidata:Q83010722
Mol file:103688-00-2.mol

Synonyms:BRN 5619905;2H-Pyrazolo(4,3-c)quinoline-2-ethanol, 4,6-dihydro-5-((4-methylphenyl)sulfonyl)-;103688-00-2;4,6-Dihydro-5-((4-methylphenyl)sulfonyl)-2H-pyrazolo(4,3-c)quinoline-2-ethanol;DTXSID50146003

Suppliers and Price of 2H-Pyrazolo(4,3-c)quinoline-2-ethanol, 4,6-dihydro-5-((4-methylphenyl)sulfonyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2H-Pyrazolo(4,3-c)quinoline-2-ethanol, 4,6-dihydro-5-((4-methylphenyl)sulfonyl)-

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:369.11471265
Heavy Atom Count:26
Complexity:585

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)N2CC3=CN(N=C3C4=CC=CC=C42)CCO

Technology Process of 2H-Pyrazolo(4,3-c)quinoline-2-ethanol, 4,6-dihydro-5-((4-methylphenyl)sulfonyl)-

There total 2 articles about 2H-Pyrazolo(4,3-c)quinoline-2-ethanol, 4,6-dihydro-5-((4-methylphenyl)sulfonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 109-84-2
2-hydroxyethylhydrazine

: 19596-46-4
3-[1-Hydroxy-meth-(E)-ylidene]-1-(toluene-4-sulfonyl)-2,3-dihydro-1H-quinolin-4-one

: 103688-00-2
2-[5-(Toluene-4-sulfonyl)-4,5-dihydro-pyrazolo[4,3-c]quinolin-2-yl]-ethanol

Guidance literature:: With acetic acid; In ethanol; Heating;

Reference yield:

: 14278-37-6
1-tosyl-2,3-dihydroquinolin-4(1H)-one

: 103688-00-2
2-[5-(Toluene-4-sulfonyl)-4,5-dihydro-pyrazolo[4,3-c]quinolin-2-yl]-ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) benzene, 10 deg C, 15 min , 2.) benzene, a) 10 deg C, b) room temperature

2: 55 percent / AcOH / ethanol / Heating

With sodium hydride; acetic acid; In ethanol;