2-(1,3-Dioxolan-2-yl)ethanol

Base Information

• Chemical Name: 2-(1,3-Dioxolan-2-yl)ethanol
• CAS No.: 5465-08-7
• Molecular Formula: C5H10 O3
• Molecular Weight: 118.133
• European Community (EC) Number: 868-406-8
• NSC Number: 28933
• DSSTox Substance ID: DTXSID80282948
• Wikidata: Q82017351
• Mol file: 5465-08-7.mol

Synonyms:2-(1,3-dioxolan-2-yl)ethanol;5465-08-7;1,3-Dioxolane-2-ethanol;2-(1,3-dioxolan-2-yl)ethan-1-ol;MFCD25964441;NSC28933;SCHEMBL526487;DTXSID80282948;BEMQPBBHOUTOIO-UHFFFAOYSA-N;2-(2-Hydroxyethyl)-1,3-dioxolane;NSC-28933;AKOS016353162;NS-01023;CS-0217470;EN300-748829;W16263

Chemical Property of 2-(1,3-Dioxolan-2-yl)ethanol

Chemical Property:

• Vapor Pressure: 0.143mmHg at 25°C
• Boiling Point: 190.9°Cat760mmHg
• Flash Point: 86.1°C
• Density: 1.115g/cm³
• XLogP3: -0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 118.062994177
• Heavy Atom Count: 8
• Complexity: 58.7

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COC(O1)CCO

Technology Process of 2-(1,3-Dioxolan-2-yl)ethanol

There total 5 articles about 2-(1,3-Dioxolan-2-yl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

2-(2-benzyloxyethyl)-1,3-dioxolane (71516-49-9) → 2-(β-Hydroxyethyl)-1,3-dioxolane (5465-08-7)

Guidance literature:

With sodium; In tetrahydrofuran; ammonia;

DOI:10.1039/P19860000889

Reference yield: 40.0%

2-(2-chloroethyl)-1,3-dioxolane (4362-36-1) → 2-(β-Hydroxyethyl)-1,3-dioxolane (5465-08-7)

Guidance literature:

With sodium hydroxide; sodium carbonate; In water; at 160 ℃; for 6h; Heating;

Reference yield:

2-bromo-2-(2-ethyl)dioxolane (18742-02-4) → 2-(β-Hydroxyethyl)-1,3-dioxolane (5465-08-7)

Guidance literature:

In benzene;

upstream raw materials:

2-(2-chloroethyl)-1,3-dioxolane

2-vinyl-1,3-dioxolane

2-(2-benzyloxyethyl)-1,3-dioxolane

2-bromo-2-(2-ethyl)dioxolane

Downstream raw materials:

6-O-allyl-5-[2-(1,3-dioxolane-2-yl)-ethyloxy]-ethyl-2,2,7,8-chroman-6-ol

5-[2-(1,3-dioxolane-2-yl)-ethyloxy]-methyl-2,2,7,8-tetramethyl-chroman-6-ol

2-(2-benzyloxyethyl)-1,3-dioxolane

((E)-3-Bicyclo[2.2.1]hepta-2,5-dien-7-yl-1-[1,3]dioxolan-2-ylmethyl-allyloxy)-tert-butyl-dimethyl-silane

Refernces

• 1、 -. "Aminopolycarboxylic acids and derivatives thereof". . . Retrieved 2008/06/13.
• 2、 Baxter, Anthony D.,Binns, Falmai,Javed, Tariq,Roberts, Stanley M.,Sadler, Peter,et al.. "Synthesis and Use of 7-Substituted Norbornadienes for the Preparation of Prostaglandins and Prostanoids". . p. 889 - 900. Retrieved 2007/10/02.