Benzyl 4-(1-(tert-butoxycarbonyl)piperidin-4-yl)piperazine-1-carboxylate

Base Information

Chemical Name:Benzyl 4-(1-(tert-butoxycarbonyl)piperidin-4-yl)piperazine-1-carboxylate
CAS No.:177276-40-3
Molecular Formula:C22H33N3O4
Molecular Weight:403.522
Hs Code.:2933599090
DSSTox Substance ID:DTXSID00597001
Wikidata:Q82492451
Mol file:177276-40-3.mol

Synonyms:177276-40-3;benzyl 4-(1-(tert-butoxycarbonyl)piperidin-4-yl)piperazine-1-carboxylate;benzyl 4-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]piperazine-1-carboxylate;benzyl 4-{1-[(tert-butoxy)carbonyl]piperidin-4-yl}piperazine-1-carboxylate;Benzyl 4-[1-(tert-butoxycarbonyl)piperidin-4-yl]piperazine-1-carboxylate;AWXFBUDOYXNHHK-UHFFFAOYSA-N;SCHEMBL310136;DTXSID00597001;J-519796;benzyl 4-(1-t-butoxycarbonylpiperidin-4-yl)piperazine 1-carboxylate;benzyl 4-(1-t-butoxycarbonylpiperidin-4-yl)piperazine-1-carboxylate;Benzyl 4-(1-tert-butoxycarbonylpiperidin-4-yl)piperazine-1-carboxylate;benzyl4-(1-(tert-butoxycarbonyl)piperidin-4-yl)piperazine-1-carboxylate;4-(1-tert-Butoxycarbonyl-piperidin-4-yl)-piperazine-1-carboxylic acid benzyl ester;Phenylmethyl 4-(1-{[(1,1-dimethylethyl)oxy]carbonyl}-4-piperidinyl)-1-piperazinecarboxylate

Suppliers and Price of Benzyl 4-(1-(tert-butoxycarbonyl)piperidin-4-yl)piperazine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Benzyl4-(1-(tert-butoxycarbonyl)piperidin-4-yl)piperazine-1-carboxylate 95+%
1g
$ 668.00

Chemenu
benzyl4-(1-(tert-butoxycarbonyl)piperidin-4-yl)piperazine-1-carboxylate 95%
1g
$ 632.00

American Custom Chemicals Corporation
BENZYL-4-(1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)PIPERAZINE-1-CARBOXYLATE 95.00%
5MG
$ 505.68

Alichem
Benzyl4-(1-(tert-butoxycarbonyl)piperidin-4-yl)piperazine-1-carboxylate
1g
$ 544.00

Total 8 raw suppliers

Chemical Property of Benzyl 4-(1-(tert-butoxycarbonyl)piperidin-4-yl)piperazine-1-carboxylate

Chemical Property:

PSA：62.32000
LogP:3.15400
Storage Temp.:2-8°C
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:403.24710654
Heavy Atom Count:29
Complexity:541

Purity/Quality:

98%min ^*data from raw suppliers

Benzyl4-(1-(tert-butoxycarbonyl)piperidin-4-yl)piperazine-1-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(CC1)N2CCN(CC2)C(=O)OCC3=CC=CC=C3

Technology Process of Benzyl 4-(1-(tert-butoxycarbonyl)piperidin-4-yl)piperazine-1-carboxylate

There total 3 articles about Benzyl 4-(1-(tert-butoxycarbonyl)piperidin-4-yl)piperazine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 31166-44-6
phenylmethyl 1-piperazinecarboxylate

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 177276-40-3
4-(1-tert-butoxycarbonylpiperidin-4-yl)piperazine-1-carboxylic acid benzyl ester

Guidance literature:: phenylmethyl 1-piperazinecarboxylate; N-tert-butyloxycarbonylpiperidin-4-one; With acetic acid; In 1,2-dichloro-ethane; at 20 ℃; for 1h;

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃; Inert atmosphere;

Reference yield: 30.0%

: 177276-40-3
4-(1-tert-butoxycarbonylpiperidin-4-yl)piperazine-1-carboxylic acid benzyl ester

Guidance literature:

Reference yield: 29.6%

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 501-53-1,94274-21-2
benzyl chloroformate

: 177276-40-3
4-(1-tert-butoxycarbonylpiperidin-4-yl)piperazine-1-carboxylic acid benzyl ester

Guidance literature:: phenylmethyl 1-piperazinecarboxylate; N-tert-butyloxycarbonylpiperidin-4-one; With hydrogen; acetic acid; palladium 10% on activated carbon; In methanol; for 96h;

benzyl chloroformate; With sodium hydrogencarbonate; In water; acetone; at 0 ℃; for 3.5h;