2-Propen-1-one, 3-(dimethylamino)-1-(2-hydroxyphenyl)-

Base Information

• Chemical Name: 2-Propen-1-one, 3-(dimethylamino)-1-(2-hydroxyphenyl)-
• CAS No.: 1776-08-5
• Molecular Formula: C11H13NO2
• Molecular Weight: 191.23
• Mol file: 1776-08-5.mol

Synonyms:3-(dimethylamino)-1-(2-hydroxyphenyl)prop-2-en-1-one;3-(dimethylamino)-1-(2-hydroxyphenyl)-prop-2-en-1-one;1-(2-hydroxyphenyl)-3-(N,N-dimethylamino)propenone;1-(2-hydroxyphenyl)-3-N,N-dimethylaminoprop-2-ene-1-one;3-(dimethylamino)-1-(1-hydroxyphen-2-yl)prop-2-en-1-one;3-(dimethylamino)-1-(2-hydroxyphenyl)-2-propen-1-one;

Chemical Property of 2-Propen-1-one, 3-(dimethylamino)-1-(2-hydroxyphenyl)-

Chemical Property:

• Melting Point: 123 °C(Solv: xylene (1330-20-7))
• Boiling Point: 310.6±42.0 °C(Predicted)
• PSA: 40.54000
• Density: 1.126±0.06 g/cm3(Predicted)
• LogP: 1.65020

Purity/Quality:

99%, ^*data from raw suppliers

(2E)-3-(Dimethylamino)-1-(2-hydroxyphenyl)-2-propen-1-one 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Propen-1-one, 3-(dimethylamino)-1-(2-hydroxyphenyl)-

There total 12 articles about 2-Propen-1-one, 3-(dimethylamino)-1-(2-hydroxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

o-hydroxyacetophenone (118-93-4,104809-67-8) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 1-(2-hydroxyphenyl)-3-dimethylaminoprop-2-enone (106129-86-6,1776-08-5)

Guidance literature:

In 2,4-dichlorophenoxyacetic acid dimethylamine; for 1h; Reflux;

DOI:10.1016/j.tetlet.2012.05.031

Reference yield: 100.0%

o-hydroxyacetophenone (118-93-4,104809-67-8) + N,N-dimethyl-formamide dimethyl acetal (4637-24-5) → 1-(2-hydroxyphenyl)-3-dimethylaminoprop-2-enone (106129-86-6,1776-08-5)

Guidance literature:

at 115 ℃; for 0.00416667h; Microwave irradiation; Inert atmosphere;

DOI:10.1016/j.tet.2009.07.021

Reference yield: 99.0%

o-hydroxyacetophenone (118-93-4,104809-67-8) + N,N-dimethyl-formamide dimethyl acetal (4637-24-5) → (E)-3-(dimethylamino)-1-(2-hydroxyphenyl)prop-2-en-1-one (1776-08-5)

Guidance literature:

for 0.0166667h; microwave irradiation;

DOI:10.3390/12082061

upstream raw materials:

chromone-3-carboxylic acid

dimethyl amine

o-hydroxyacetophenone

N,N-dimethyl-formamide dimethyl acetal

Downstream raw materials:

3-bromo-4H-chromen-4-one