N-(1-NAPHTHALEN-2-YL-VINYL)-ACETAMIDE

Base Information

• Chemical Name: N-(1-NAPHTHALEN-2-YL-VINYL)-ACETAMIDE
• CAS No.: 177750-24-2
• Molecular Formula: C14H13NO
• Molecular Weight: 211.263
• Mol file: 177750-24-2.mol

Synonyms:N-(1-(2-naphthyl)vinyl)acetamide;N-[1-(2-naphthyl)vinyl]acetamide;N-(1-Naphthalen-2-yl-vinyl)-acetamide;N-(1-naphth-2-ylvinyl)acetamide;N-[1-(naphthalen-2-yl)vinyl]acetamide;N-acetyl-1-(2-naphthyl)ethenamine;

Chemical Property of N-(1-NAPHTHALEN-2-YL-VINYL)-ACETAMIDE

Chemical Property:

• Melting Point: 119 - 121 °C
• PSA: 29.10000
• LogP: 3.33750

Purity/Quality:

99% ^*data from raw suppliers

N-(1-(Naphthalen-2-yl)vinyl)acetamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(1-NAPHTHALEN-2-YL-VINYL)-ACETAMIDE

There total 11 articles about N-(1-NAPHTHALEN-2-YL-VINYL)-ACETAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

acetic anhydride (108-24-7) + 2-(1-azidoethyl)naphthalene (120342-65-6) → N-(1-(naphthalen-2-yl)vinyl)acetamide (177750-24-2)

Guidance literature:

With di[(2,4-bis-tert-butyl-1-methoxy-3-neopentylcyclopentadienyl)dichlororuthenium(III)]; triethylamine; 1-butyl-3-methylimidazolium chloride; at 70 ℃; for 3h; Inert atmosphere;

DOI:10.1002/cctc.201500935

Reference yield: 85.0%

2-acetonaphthone oxime (100485-52-7,100485-60-7,51674-06-7) + acetic anhydride (108-24-7) + phenylacetylene (536-74-3) → 1,4-diphenyl-1,3-butadiyne (886-66-8) + N-(1-(naphthalen-2-yl)vinyl)acetamide (177750-24-2)

Guidance literature:

With pyridine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In 1,2-dichloro-ethane; at 120 ℃; for 5h; Inert atmosphere; Green chemistry;

DOI:10.1016/S1872-2067(14)60220-5

Reference yield: 85.0%

2-acetonaphthone oxime (100485-52-7,100485-60-7,51674-06-7) + acetic anhydride (108-24-7) + acetic acid (64-19-7,77671-22-8) → N-(1-(naphthalen-2-yl)vinyl)acetamide (177750-24-2)

Guidance literature:

With sodium dithionite; iron(II) acetate; potassium iodide; In 1,2-dichloro-ethane; at 120 ℃; for 0.5h; Inert atmosphere;

DOI:10.1016/j.tetlet.2019.05.006

upstream raw materials:

2-acetonaphthone oxime

acetic anhydride

acetylaminoethylene

2-naphthyl triflate

Downstream raw materials:

methyl 2-naphthyl ketone

bis(4-methoxyphenyl) (R)-2-(1-(naphthalen-2-yl)-1-oxopentan-3-yl)malonate

bis(4-methoxyphenyl) (R)-2-(4-(naphthalen-2-yl)-4-oxobutan-2-yl)malonate

1-(5-(naphthalen-2-yl)-2,3-diphenyl-1H-pyrrol-1-yl)ethanone