4-Phenyl-5-((quinolin-8-yloxy)methyl)-4H-1,2,4-triazole-3-thiol

Base Information

Chemical Name:4-Phenyl-5-((quinolin-8-yloxy)methyl)-4H-1,2,4-triazole-3-thiol
CAS No.:73511-58-7
Molecular Formula:C18H14 N4 O S
Molecular Weight:334.401
Hs Code.:
NSC Number:345722
DSSTox Substance ID:DTXSID40349920

Synonyms:73511-58-7;4-Phenyl-5-((quinolin-8-yloxy)methyl)-4H-1,2,4-triazole-3-thiol;4-Phenyl-5-(quinolin-8-yloxymethyl)-4H-[1,2,4]triazole-3-thiol;4-phenyl-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazole-3-thiol;NSC345722;ST042108;Oprea1_121550;Oprea1_542918;DTXSID40349920;4-phenyl-3-(quinolin-8-yloxymethyl)-1H-1,2,4-triazole-5-thione;CCG-24875;STK734130;AKOS000567739;NSC-345722;CS-0322515;EU-0050418

Suppliers and Price of 4-Phenyl-5-((quinolin-8-yloxy)methyl)-4H-1,2,4-triazole-3-thiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-Phenyl-5-((quinolin-8-yloxy)methyl)-4H-1,2,4-triazole-3-thiol

Chemical Property:

Vapor Pressure:1.77E-10mmHg at 25°C
Boiling Point:509°C at 760 mmHg
Flash Point:261.6°C
Density:1.34g/cm³
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:334.08883226
Heavy Atom Count:24
Complexity:491

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)N2C(=NNC2=S)COC3=CC=CC4=C3N=CC=C4

Technology Process of 4-Phenyl-5-((quinolin-8-yloxy)methyl)-4H-1,2,4-triazole-3-thiol

There total 5 articles about 4-Phenyl-5-((quinolin-8-yloxy)methyl)-4H-1,2,4-triazole-3-thiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 65625-13-0
N-phenyl-2-[2-((quinolin-8-yloxy)acetyl)hydrazine-1-carbothioamide]

: 73511-58-7
4-phenyl-5-[((quinolin-8-yloxy)methyl)-4H-1,2,4-triazole-3-thiol]

Guidance literature:: With sodium hydroxide; for 3h; Reflux;
DOI:10.1080/10426507.2016.1247087

Reference yield:

: 3281-08-1
8-quinolinoxyacetic acid hydrazide

: 73511-58-7
4-phenyl-5-[((quinolin-8-yloxy)methyl)-4H-1,2,4-triazole-3-thiol]

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 4 h / Reflux

2: sodium hydroxide / 3 h / Reflux

With sodium hydroxide; In ethanol;
DOI:10.1080/10426507.2016.1247087

Reference yield:

: 42322-30-5
ethyl 2-(quinolin-8-yloxy)acetate

: 73511-58-7
4-phenyl-5-[((quinolin-8-yloxy)methyl)-4H-1,2,4-triazole-3-thiol]

Guidance literature:: Multi-step reaction with 3 steps

1: hydrazine hydrate / ethanol

2: ethanol / 4 h / Reflux

3: sodium hydroxide / 3 h / Reflux

With hydrazine hydrate; sodium hydroxide; In ethanol;
DOI:10.1080/10426507.2016.1247087