Boc-lys(Z)-OH dcha

Base Information

• Chemical Name: Boc-lys(Z)-OH dcha
• CAS No.: 16948-04-2
• Molecular Formula: C19H28N2O6^.C12H23N
• Molecular Weight: 561.762
• Hs Code.: 29224985
• European Community (EC) Number: 241-018-0
• DSSTox Substance ID: DTXSID10937636
• Mol file: 16948-04-2.mol

Synonyms:16948-04-2;BOC-LYS(Z)-OH DCHA;Boc-Lys(Z)-OH (dicyclohexylammonium) salt;Boc-Lys(Z)-OH (DCHA);Dicyclohexylamine (S)-6-(((benzyloxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)hexanoate;EINECS 241-018-0;N-cyclohexylcyclohexanamine;(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-6-(phenylmethoxycarbonylamino)hexanoic acid;N6-((Benzyloxy)carbonyl)-N2-((tert-butoxy)carbonyl)-L-lysine, compound with dicyclohexylamine (1:1);N6-[(benzyloxy)carbonyl]-N2-[(tert-butoxy)carbonyl]-L-lysine, compound with dicyclohexylamine (1:1);C19H28N2O6.C12H23N;D06NXC;N6-[(Benzyloxy)carbonyl]-N2-[(tert-butoxy)carbonyl]-L-lysine dicyclohexylamine;DTXSID10937636;BQERJWRZLXZNIO-RSAXXLAASA-N;MFCD00066511;AKOS015901342;HY-W109513;BS-23494;CS-0163035;C19-H28-N2-O6.C12-H23-N;D94734;A811109;J-010546;Boc-Lys(Z)-OH (dicyclohexylammonium) salt, >=99.0% (NT);dicyclohexylamine N6-((benzyloxy)carbonyl)-N2-(tert-butoxycarbonyl)-L-lysinate;Dicyclohexylamine(S)-6-(((benzyloxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)hexanoate;N~6~-[(Benzyloxy)(hydroxy)methylidene]-N~2~-[tert-butoxy(hydroxy)methylidene]lysine--N-cyclohexylcyclohexanamine (1/1)

Chemical Property of Boc-lys(Z)-OH dcha

Chemical Property:

• Appearance/Colour: white fine crystalline powder
• Vapor Pressure: 1.26E-14mmHg at 25°C
• Melting Point: 114-116 °C
• Boiling Point: 587 °C at 760 mmHg
• Flash Point: 308.8 °C
• PSA: 125.99000
• LogP: 7.47510
• Storage Temp.: -20°C
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 14
• Exact Mass: 561.37778636
• Heavy Atom Count: 40
• Complexity: 599

Purity/Quality:

99% ^*data from raw suppliers

N-alpha-Boc-Nε-Z-L-lysine dicyclohexylammonium salt ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(C)(C)OC(=O)NC(CCCCNC(=O)OCC1=CC=CC=C1)C(=O)O.C1CCC(CC1)NC2CCCCC2
• Isomeric SMILES: CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCC1=CC=CC=C1)C(=O)O.C1CCC(CC1)NC2CCCCC2

Technology Process of Boc-lys(Z)-OH dcha

There total 1 articles about Boc-lys(Z)-OH dcha which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Nα-tert-butyloxycarbonyl-Nε-benzyloxycarbonyllysine dicyclohexylammonium salt (16948-04-2,76477-42-4)

Guidance literature:

N^ε-Benzyloxycarbonyllysin, tert.-Butyl-azidoformiat;

Reference yield: 94.0%

methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride (5680-80-8) + Nα-tert-butyloxycarbonyl-Nε-benzyloxycarbonyllysine dicyclohexylammonium salt (16948-04-2,76477-42-4) → Boc-Lys(Z)-Ser-OMe (84983-66-4)

Guidance literature:

With 4-methyl-morpholine; benzotriazol-1-ol; In tetrahydrofuran; at 4 ℃; for 16h;

DOI:10.1248/cpb.30.4448

Reference yield: 93.0%

Nα-tert-butyloxycarbonyl-Nε-benzyloxycarbonyllysine dicyclohexylammonium salt (16948-04-2,76477-42-4) + Asp(OcHex)-Val-NHNH-Troc → Boc-Lys(Z)-Asp(OcHex)-Val-NHNH-Troc (112157-55-8)

Guidance literature:

With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In N,N-dimethyl-formamide;

DOI:10.1248/cpb.35.2016

Downstream raw materials:

Boc-Lys(Z)-Lys(Z)-OBzl

Boc-Lys(Z)-Ser-OMe

N^α-tert-butyloxycarbonyl-N^ε-benzyloxycarbonyllysyl-alanyl-leucine methyl ester

Boc-Lys(Z)-Asn-ONb