84983-66-4Relevant academic research and scientific papers
Regioselective synthesis of antiparallel loops on a macrocyclic scaffold constrained by oxazoles and thiazoles
Singh, Yogendra,Stoermer, Martin J.,Lucke, Andrew J.,Glenn, Matthew P.,Fairlie, David P.
, p. 3367 - 3370 (2007/10/03)
(matrix presented) The regioselective syntheses and structures are reported for two tris-macrocylic compounds, each possessing two antiparallel loops on a macrocyclic scaffold constrained by two oxazoles and two thiazoles. NMR solution structures show the
Amino acids and peptides. IX. Synthesis of cysteine-containing peptide fragments related to human hepatic metallothionein II (hMT II) and determination of their heavy metal-binding properties
Ohta,Okada,Tanaka
, p. 3094 - 3103 (2007/10/02)
Eight kinds of cysteine-containing peptides related to human hepatic metallothionein were synthesized by conventional methods. The metal-binding properties of these peptides with Zn2+ and Cd2+ were indicated by an increase of ultraviolet absorbance resulting from mercaptide formation. The Cd-binding activities of various peptides obtained here were assessed by measuring the increase in absorbance of mercaptide at 250 mm as a function of the concentration of Cd. The binding abilities of the peptides with Cd differed substantially.
