Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl -

Base Information

• Chemical Name: Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl -
• CAS No.: 182496-00-0
• Molecular Formula: C34H39N3O8
• Molecular Weight: 617.699
• Mol file: 182496-00-0.mol

Synonyms:5'-O-dimethoxytrityl-2'-O-(2-methoxyethyl)-5-methyl-cytidine;5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methylcytidine;2'-O-methoxyethyl-5'-O-(4,4'-dimethoxytrityl)-5-methylcytidine;2'--O--Methoxyethyl-5'--O--dimethoxytrityl-5-methylcytidine;5'-O-4,4'-dimethoxytrityl-2'-O-(2-methoxyethyl)-5-methylcytidine;5'-O-dimethoxytrityl-2'-O-(2-methoxyethyl)-5-methylcytidine;

Chemical Property of Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl -

Chemical Property:

• PSA: 136.52000
• LogP: 4.03090

Purity/Quality:

99% ^*data from raw suppliers

5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl -

There total 18 articles about Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl - which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3'-O-acetyl-2'-O-methoxyethyl-5'-O-(4,4'-dimethoxytrityl)-5-methyl-4-triazoleuridine (182495-99-4) → 2'-O-methoxyethyl-5'-O-dimethoxytrityl-5-methylcytidine (182496-00-0)

Guidance literature:

3'-O-acetyl-2'-O-methoxyethyl-5'-O-(4,4'-dimethoxytrityl)-5-methyl-4-triazoleuridine; With ammonia; water; In 1,4-dioxane; at 20 ℃; for 2h;

With ammonia; In methanol; at 100 ℃; for 2h;

Reference yield: 95.0%

3'-O-acetyl-2'-O-methoxyethyl-5'-O-dimethoxytrityl-5-methyl-4-triazoleuridine (256489-97-1) → 2'-O-methoxyethyl-5'-O-dimethoxytrityl-5-methylcytidine (182496-00-0)

Guidance literature:

3'-O-acetyl-2'-O-methoxyethyl-5'-O-dimethoxytrityl-5-methyl-4-triazoleuridine; With ammonium hydroxide; In 1,4-dioxane; at 20 ℃; for 2h;

With ammonia; In methanol; at 100 ℃; for 2h;

Reference yield: 95.0%

3'-O-acetyl-2'-O-methoxyethyl-5'-O-dimethoxytrityl-5-methyl-4-triazoleuridine (195253-09-9) → 2'-O-methoxyethyl-5'-O-dimethoxytrityl-5-methylcytidine (182496-00-0)

Guidance literature:

3'-O-acetyl-2'-O-methoxyethyl-5'-O-dimethoxytrityl-5-methyl-4-triazoleuridine; With ammonia; In 1,4-dioxane; water; at 20 ℃; for 2h;

With ammonia; In methanol; at 100 ℃; for 2h;

upstream raw materials:

3'-O-acetyl-2'-O-methoxyethyl-5'-O-(4,4'-dimethoxytrityl)-5-methyl-4-triazoleuridine

5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-5-methyluridine

O-2,2'-cyclo-5-methyluridine

4,4'-dimethoxytrityl chloride

Downstream raw materials:

C₅₀H₅₉N₄O₁₀P

C₃₈H₄₅N₃O₉

MOE 5-Me-C Amidite

5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N₄-benzoyl-5-methylcytidine