Azetidin-3-YL-acetic acid

Base Information

Chemical Name:Azetidin-3-YL-acetic acid
CAS No.:183062-92-2
Molecular Formula:C5H9NO2
Molecular Weight:115.13000
Hs Code.:2933990090
ChEMBL ID:CHEMBL1165238
DSSTox Substance ID:DTXSID10472017
Mol file:183062-92-2.mol

Synonyms:AZETIDIN-3-YL-ACETIC ACID;183062-92-2;3-Azetidineacetic acid;2-(azetidin-3-yl)acetic Acid;Azetidine-3-acetic acid;azetidin-3-ylacetic acid;azetidine-3-ylacetic acid;(azetidin-3-yl)acetic acid;SCHEMBL2569289;AZETIDIN-3-YL-ACETICACID;CHEMBL1165238;DTXSID10472017;SCBDSTCOJNNUCN-UHFFFAOYSA-N;AMY38757;MFCD09998940;AKOS006302846;PB17729;AS-50697;CS-0053737;EN300-83196;P10897;A812744;F8887-4133

Suppliers and Price of Azetidin-3-YL-acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Azetidine-3-aceticacid 95+%
1g
$ 2014.00

Crysdot
Azetidin-3-yl-aceticacid 95+%
1g
$ 475.00

Chemenu
Azetidine-3-aceticacid 95%
1g
$ 444.00

American Custom Chemicals Corporation
AZETIDIN-3-YL-ACETIC ACID 95.00%
5MG
$ 502.29

Total 17 raw suppliers

Chemical Property of Azetidin-3-YL-acetic acid

Chemical Property:

Vapor Pressure:0.004mmHg at 25°C
Boiling Point:259.725oC at 760 mmHg
Flash Point:110.878oC
PSA：49.33000
Density:1.16g/cm3
LogP:0.00930
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:-3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:115.063328530
Heavy Atom Count:8
Complexity:98.6

Purity/Quality:

97% ^*data from raw suppliers

Azetidine-3-aceticacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(CN1)CC(=O)O

Technology Process of Azetidin-3-YL-acetic acid

There total 4 articles about Azetidin-3-YL-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 183062-96-6
2-(1-(tert-butoxycarbonyl)azetidin-3-yl)acetic acid

: 183062-92-2
azetidin-3-ylacetic acid

Guidance literature:: With trifluoroacetic acid; for 1h; Ambient temperature;

Reference yield:

: 181941-94-6
diethyl 2-[1-(diphenylmethyl)azetidin-3-yl]propane-1,3-dioate

: 183062-92-2
azetidin-3-ylacetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 99 percent / H₂ / 20percent Pd(OH)2 on C / ethyl acetate / 14 h / 760 Torr

2: 89 percent / aq. KOH / ethanol / 20 h / Ambient temperature

3: 23 percent / 0.17 h / 160 - 170 °C / 1 Torr

4: 88 percent / TFA / 1 h / Ambient temperature

With potassium hydroxide; hydrogen; trifluoroacetic acid; palladium hydroxide - carbon; In ethanol; ethyl acetate;

Reference yield:

: 183062-95-5
Diethyl-2-(1-(tert-butoxycarbonyl)azetidin-3-yl)malonate

: 183062-92-2
azetidin-3-ylacetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / aq. KOH / ethanol / 20 h / Ambient temperature

2: 23 percent / 0.17 h / 160 - 170 °C / 1 Torr

3: 88 percent / TFA / 1 h / Ambient temperature

With potassium hydroxide; trifluoroacetic acid; In ethanol;