183062-96-6

Basic information

• Product Name: N-Boc-3-azetidine acetic acid
• Synonyms: 3-Azetidineacetic acid, 1-[(1,1-diMethylethoxy)carbonyl]-;[1-(tert-Butoxycarbonyl)azetidin-3-yl]acetic acid;2-(1-(boc)azetidin-3-yl)acetic acid;2-[1-[(2-methylpropan-2-yl)oxycarbonyl]azetidin-3-yl]acetic acid;1-Boc-3-azetidine acetic acid;1-Boc-3-azetidineacetic a...
• CAS NO: 183062-96-6
• Molecular Formula: C₁₀H₁₇NO₄
• Molecular Weight: 215.25
• Mol File: 183062-96-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 118 °C
• Boiling Point: 341.628 °C at 760 mmHg
• Flash Point: 160.411 °C
• Appearance: /
• Density: 1.186 g/cm³
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 4.58±0.10(Predicted)
• CAS DataBase Reference: N-Boc-3-azetidine acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-Boc-3-azetidine acetic acid(183062-96-6)
• EPA Substance Registry System: N-Boc-3-azetidine acetic acid(183062-96-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• RIDADR: UN2811
• WGK Germany: 3
• Hazardous Substances Data: 183062-96-6(Hazardous Substances Data)

Usage

General Description

N-Boc-3-azetidine acetic acid is a chemical compound with the formula C11H17NO4. It is a derivative of azetidine, which is a four-membered heterocyclic ring containing one nitrogen atom. The N-Boc-3-azetidine acetic acid is commonly used as a building block for the synthesis of various pharmaceuticals and biologically active compounds. The N-Boc group, or tert-butoxycarbonyl group, serves as a protecting group for the amine functionality, allowing for selective reactions while keeping the amine group intact. The acetic acid portion of the molecule provides a carboxylic acid functionality, which can participate in various chemical reactions. N-Boc-3-azetidine acetic acid is an important intermediate in organic synthesis due to its versatility and reactivity.

Upstream product

• 158602-35-8 tert-butyl 3-(2-ethoxy-2-oxoethyl)azetidine-1-carboxylate 
• 1002355-96-5 tert-butyl 3-(2-ethoxy-2-oxoethylidene)azetidine-1-carboxylate 
• 183062-95-5 Diethyl-2-(1-(tert-butoxycarbonyl)azetidin-3-yl)malonate 
• 183062-97-7 2-(1-tert-Butoxycarbonyl-azetidin-3-yl)-malonic acid 
• 398489-26-4 tert-butyl 3-oxoazetidine-1-carboxylate 
• 497160-14-2 tert-butyl 3-(2-methoxy-2-oxo-ethyl)azetidine-1-carboxylate 
• 181941-94-6 diethyl 2-[1-(diphenylmethyl)azetidin-3-yl]propane-1,3-dioate 

Downstream Products

• 152537-03-6 tert-butyl 3-(2-hydroxyethyl)azetidine-1-carboxylate 
• 1620087-79-7 3-(2-(3,4-dichlorophenyl)-2-(2-fluorophenoxy)ethyl)azetidine 
• 1629248-01-6 C₂₂H₂₄Cl₃NO₃ 
• 1620087-53-7 C₂₂H₂₄Cl₂FNO₃ 
• 1620087-54-8 C₂₂H₂₅Cl₂NO₃ 
• 1620087-55-9 C₂₃H₂₇Cl₂NO₃ 
• 1620087-56-0 C₂₃H₂₇Cl₂NO₃ 
• 1620087-80-0 3-(2-(3,4-dichlorophenyl)-2-phenoxyethyl)azetidine 
• 1629248-02-7 C₂₂H₂₄Cl₃NO₃ 
• 1629248-07-2 C₂₃H₂₇Cl₂NO₃ 
• 1629248-08-3 C₂₂H₂₄Cl₃NO₃ 
• 1620087-58-2 C₂₂H₂₃Cl₄NO₃ 
• 1620087-59-3 C₂₂H₂₃Cl₂F₂NO₃ 
• 1620087-60-6 C₂₂H₂₄Cl₂FNO₃ 

Relevant articles and documents

COMPOUNDS AND USES THEREOF

The present disclosure features compounds and methods useful for the treatment of BAF complex-related disorders.

PYRAZOLONE DERIVATIVE HAVING CYCLIC SIDE CHAIN

PROBLEM TO BE SOLVED: To provide a compound that has excellent inhibitory action on ATPase activity of TIP48/TIP49 complex and is therefore useful for the treatment of tumor, or a pharmacologically acceptable salt thereof. SOLUTION: The present invention provides a compound having a structure represented by general formula (I), its pharmacologically acceptable salt, or a pharmaceutical composition comprising the compound (where R1, R2, R3, R4, R5, R6, R7, W, and Z are as defined in the specifications). SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT

A Straightforward Synthesis of Azetidin-3-ylacetic Acid

The preparation of azetidin-3-ylacetic acid from epichlorohydrin via diethyl 2-[1-(diphenylmethyl)azetidin-3-yl] propane-1,3-dioate is described.