Triethoxy(2-methylphenyl)silane

Base Information

• Chemical Name: Triethoxy(2-methylphenyl)silane
• CAS No.: 18412-55-0
• Molecular Formula: C13H22O3Si
• Molecular Weight: 254.401
• DSSTox Substance ID: DTXSID30545530
• Nikkaji Number: J1.634.895C
• Wikidata: Q82423058
• Mol file: 18412-55-0.mol

Synonyms:triethoxy(o-tolyl)silane;18412-55-0;triethoxy(2-methylphenyl)silane;SCHEMBL109759;DTXSID30545530;MFCD11554869

Chemical Property of Triethoxy(2-methylphenyl)silane

Chemical Property:

• PSA: 27.69000
• LogP: 2.25040
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 254.13382109
• Heavy Atom Count: 17
• Complexity: 194

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCO[Si](C1=CC=CC=C1C)(OCC)OCC

Technology Process of Triethoxy(2-methylphenyl)silane

There total 5 articles about Triethoxy(2-methylphenyl)silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

ortho-methylphenyl iodide (615-37-2) + Triethoxysilane (998-30-1) → triethoxy(o-tolyl)silane (18412-55-0) + toluene (108-88-3,15644-74-3,16713-13-6)

Guidance literature:

With triethylamine; bis(acetonitrile)(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; In N,N-dimethyl-formamide; at 80 ℃; for 2h;

DOI:10.1016/j.tet.2007.02.103

Reference yield: 81.0%

ortho-methylphenyl iodide (615-37-2) + Triethoxysilane (998-30-1) → triethoxy(o-tolyl)silane (18412-55-0)

Guidance literature:

With bis(acetonitrile)(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; triethylamine; In N,N-dimethyl-formamide; at 80 ℃; for 2h;

DOI:10.1021/ol025770p

Reference yield: 77.0%

tetraethoxy orthosilicate (78-10-4) + o-tolylmagnesium bromide-lithium chloride → triethoxy(o-tolyl)silane (18412-55-0)

Guidance literature:

In tetrahydrofuran; at -30 - 10 ℃; for 8h;

DOI:10.1002/chem.201504435

upstream raw materials:

tetraethoxy orthosilicate

2-methylphenyl bromide

ortho-methylphenyl iodide

Triethoxysilane

Downstream raw materials:

o-tolylsilane

butyl (2E)-3-(2-methylphenyl)acrylate

2-methoxy-5-(2'-methylphenyl)cyclohepta-2,4,6-trien-1-one

4-cyano-2'-methyl-1,1'-biphenyl