Propanehydrazonoyl chloride, N-(4-methylphenyl)-2-oxo-

Base Information

• Chemical Name: Propanehydrazonoyl chloride, N-(4-methylphenyl)-2-oxo-
• CAS No.: 18440-55-6
• Molecular Formula: C10H11ClN2O
• Molecular Weight: 210.663
• DSSTox Substance ID: DTXSID30377954
• Mol file: 18440-55-6.mol

Synonyms:Propanehydrazonoyl chloride, N-(4-methylphenyl)-2-oxo-;N-(4-methylphenyl)-2-oxopropanehydrazonoyl chloride;18440-55-6;SCHEMBL9067934;DTXSID30377954;SZUGRZADBSQNJK-UHFFFAOYSA-N;1-chloro-1-[(4-methylphenyl-)hydrazono]-2-propanone

Chemical Property of Propanehydrazonoyl chloride, N-(4-methylphenyl)-2-oxo-

Chemical Property:

• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 210.0559907
• Heavy Atom Count: 14
• Complexity: 232

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)NN=C(C(=O)C)Cl

Technology Process of Propanehydrazonoyl chloride, N-(4-methylphenyl)-2-oxo-

There total 7 articles about Propanehydrazonoyl chloride, N-(4-methylphenyl)-2-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

p-toluidine (106-49-0,12221-03-3) + 3-chloropentane-2,4-dione (1694-29-7) → 1-chloro-1-(p-tolylhydrazone)propanone (132815-80-6,18440-55-6)

Guidance literature:

p-toluidine; With hydrogenchloride; sodium nitrite; In water; at 5 ℃; for 0.5h;

3-chloropentane-2,4-dione; With acetic acid; In water; at 5 ℃; for 2h;

DOI:10.3390/molecules26144240

Reference yield:

p-methylbenzenediazonium chloride (2028-84-4) + 3-chloropentane-2,4-dione (1694-29-7) → 1-chloro-1-(p-tolylhydrazone)propanone (132815-80-6,18440-55-6)

Guidance literature:

With acetic acid; at 0 ℃;

Reference yield:

p-methylbenzenediazonium chloride (2028-84-4) + 3-chloropentane-2,4-dione (1694-29-7) → 1-chloro-1-[(4-methylphenyl)hydrazono]propanone (18440-55-6)

Guidance literature:

With sodium acetate; In ethanol; at -5 ℃;

DOI:10.1248/bpb.b15-00439

upstream raw materials:

4-methylbenzene diazonium

HacacCl

acetic acid

p-methylbenzenediazonium chloride

Downstream raw materials:

6-acetyl-5,5-diphenyl-2-p-tolyl-2H-5λ⁵-[1,2,4,5]triazaphosphinin-3-one

C₂₁H₂₃N₅O₂

1-(5-imino-4-p-tolyl-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ethanone

1-(5-Imino-4-p-tolyl-4,5-dihydro-[1,3,4]selenadiazol-2-yl)-ethanone