N-(4-chlorophenyl)-2-oxo-2H-chromene-3-carboxamide

Base Information

Chemical Name:N-(4-chlorophenyl)-2-oxo-2H-chromene-3-carboxamide
CAS No.:1847-02-5
Molecular Formula:C16H10ClNO3
Molecular Weight:299.713
Hs Code.:
European Community (EC) Number:655-562-5
Mol file:1847-02-5.mol

Synonyms:N-(4-chlorophenyl)-2-oxo-2H-chromene-3-carboxamide;1847-02-5;N-(4-chlorophenyl)-2-oxochromene-3-carboxamide;Oprea1_232316;Oprea1_824262;STK408142;AKOS000533252;AE-641/08281054;SR-01000410416;SR-01000410416-1;Z28161980;2h-1-benzopyran-3-carboxamide,n-(4-chlorophenyl)-2-oxo-

Suppliers and Price of N-(4-chlorophenyl)-2-oxo-2H-chromene-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of N-(4-chlorophenyl)-2-oxo-2H-chromene-3-carboxamide

Chemical Property:

PSA：0.00000
LogP:0.00000
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:299.0349209
Heavy Atom Count:21
Complexity:454

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=C(C(=O)O2)C(=O)NC3=CC=C(C=C3)Cl

Technology Process of N-(4-chlorophenyl)-2-oxo-2H-chromene-3-carboxamide

There total 5 articles about N-(4-chlorophenyl)-2-oxo-2H-chromene-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 3757-06-0
coumarin 3-carboxylic acid chloride

: 106-47-8
4-chloro-aniline

: 1847-02-5
2-oxo-2H-chromene-3-carboxylic acid (4-chloro-phenyl)-amide

Guidance literature:: With sodium hydrogencarbonate; In acetone; at 20 ℃; for 10h;

Reference yield: 64.0%

: 531-81-7
2-oxo-2H-chromene-3-carboxylic acid

: 106-47-8
4-chloro-aniline

: 1847-02-5
2-oxo-2H-chromene-3-carboxylic acid (4-chloro-phenyl)-amide

Guidance literature:: 2-oxo-2H-chromene-3-carboxylic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 0.5h;

4-chloro-aniline; With triethylamine; In dichloromethane; at 20 ℃; for 12h;
DOI:10.2174/1570180816666190617150803