4-Pentynal

Base Information

• Chemical Name: 4-Pentynal
• CAS No.: 18498-59-4
• Molecular Formula: C5H6O
• Molecular Weight: 82.102
• Mol file: 18498-59-4.mol

Synonyms:Pent-4-ynal;4-pentynal;4-pentyn-1-aldehyde;pent-4-yn-al;pent-4-yn-1-al;

Chemical Property of 4-Pentynal

Chemical Property:

• Melting Point: -96.15°C (estimate)
• Refractive Index: 1.4093 (estimate)
• Boiling Point: 139.95°C (estimate)
• PSA: 17.07000
• Density: 0.8772 (estimate)
• LogP: 0.59870

Purity/Quality:

99% ^*data from raw suppliers

Pent-4-ynal ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Pentynal

There total 17 articles about 4-Pentynal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

pent-1-yn-5-ol (5390-04-5) → 4-pentyn-1-al (18498-59-4)

Guidance literature:

With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; at -78 ℃; for 1h;

DOI:10.1021/jm00109a010

Reference yield: 75.0%

methyl butynol (181878-28-4) → 4-pentyn-1-al (18498-59-4)

Guidance literature:

methyl butynol; With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; for 1h; Inert atmosphere;

With triethylamine; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.0c02079

Reference yield: 68.6%

pent-1-yn-5-ol (5390-04-5) + triethylamine (121-44-8) → 4-pentyn-1-al (18498-59-4)

Guidance literature:

pent-1-yn-5-ol; With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; at -78 ℃; for 0.25h;

triethylamine; In dichloromethane; at 0 ℃; for 0.25h;

upstream raw materials:

pent-1-yn-5-ol

cyclohexyl-pent-4-ynylidene-amine

pent-4-ynethioic acid S-butyl ester

nitrite de pentyne-4 ol-1

Downstream raw materials:

(2E,4Z)-Undeca-2,4-diene-8,10-diynoic acid phenethyl-amide

(E,E)-2,4-undecadien-8,10-diynoic acid phenethylamide

all-trans-1,2-Bis-(octa-1,3-dien-7-inyl)-benzol

trans,trans-1,2-Bis(1-hexen-5-inyl)benzol