(4-(Chloromethyl)phenyl)(piperidin-1-yl)methanone

Base Information

Chemical Name:(4-(Chloromethyl)phenyl)(piperidin-1-yl)methanone
CAS No.:185743-00-4
Molecular Formula:C13H16ClNO
Molecular Weight:237.729
Hs Code.:
European Community (EC) Number:959-308-7
DSSTox Substance ID:DTXSID70586240
Wikidata:Q82478332
Mol file:185743-00-4.mol

Synonyms:185743-00-4;(4-(chloromethyl)phenyl)(piperidin-1-yl)methanone;1-[4-(CHLOROMETHYL)BENZOYL]PIPERIDINE;(4-chloromethyl-phenyl)-piperidin-1-yl-methanone;[4-(chloromethyl)phenyl]-piperidin-1-ylmethanone;[4-(chloromethyl)phenyl](piperidin-1-yl)methanone;SCHEMBL5565832;DTXSID70586240;WVQKALIRKRBPTC-UHFFFAOYSA-N;MFCD08166734;STL301644;1-(4'-chloromethylbenzoyl)piperidine;AKOS000268887;MCULE-3625852772;LS-11983;DB-223073;F20021;A1-49267

Suppliers and Price of (4-(Chloromethyl)phenyl)(piperidin-1-yl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of (4-(Chloromethyl)phenyl)(piperidin-1-yl)methanone

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:237.0920418
Heavy Atom Count:16
Complexity:230

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)C(=O)C2=CC=C(C=C2)CCl

Technology Process of (4-(Chloromethyl)phenyl)(piperidin-1-yl)methanone

There total 4 articles about (4-(Chloromethyl)phenyl)(piperidin-1-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 110-89-4
piperidine

: 876-08-4
p-(chloromethyl)benzoyl chloride

: 185743-00-4
(4-(chloromethyl)phenyl)(piperidin-1-yl)methanone

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 24.5h;
DOI:10.1021/jm500409k

Reference yield: 92.0%

: 1-(4'-(3,4-Methylenedioxyphenoxy)-methylbenzoyl)piperidine

: 185743-00-4
(4-(chloromethyl)phenyl)(piperidin-1-yl)methanone

Guidance literature:

Reference yield: 88.0%

: 110-89-4
piperidine

: 1642-81-5
p-(chloromethyl)benzoic acid

: 185743-00-4
(4-(chloromethyl)phenyl)(piperidin-1-yl)methanone

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 6h;
DOI:10.1016/j.bmc.2018.04.048