Bis(2-methylphenyl)phosphinic acid

Base Information

• Chemical Name: Bis(2-methylphenyl)phosphinic acid
• CAS No.: 18593-19-6
• Molecular Formula: C14H15O2P
• Molecular Weight: 246.246
• Hs Code.: 2916399090
• Mol file: 18593-19-6.mol

Synonyms:Phosphinic acid,di-o-tolyl;Di-o-tolylphosphinsaeure;Bis--phosphinsaeure;

Chemical Property of Bis(2-methylphenyl)phosphinic acid

Chemical Property:

• PSA: 47.11000
• LogP: 2.52460

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Bis(2-methylphenyl)phosphinic acid

There total 12 articles about Bis(2-methylphenyl)phosphinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.3%

di-o-tolylphosphine oxide (30309-80-9) → bis(2-methylphenyl)phosphinic acid (18593-19-6)

Guidance literature:

With sodium hydroxide; dihydrogen peroxide; In water; for 0.333333h; Heating;

DOI:10.1021/jo0300183

Reference yield: 68.0%

di-o-tolylphosphine oxide (30309-80-9) → bis(2-methylphenyl)phosphoryl fluoride + bis(2-methylphenyl)phosphinic acid (18593-19-6)

Guidance literature:

With 4-(difluoroiodo)toluene; In chlorobenzene; at 60 ℃; for 0.166667h; Inert atmosphere;

DOI:10.1016/j.tetlet.2018.06.044

Reference yield: 34.0%

N-allyl-P,P-di-o-tolylphosphinic amide → bis(2-methylphenyl)phosphinic acid (18593-19-6)

Guidance literature:

N-allyl-P,P-di-o-tolylphosphinic amide; With water; monoammonium para-toluenesulfonate; o-phthalic dicarboxaldehyde; In acetonitrile; at 90 ℃; for 24h; Sealed tube;

With hydrogenchloride; In water; pH=1 - 2; chemoselective reaction;

DOI:10.1039/c7cc04950a

upstream raw materials:

2-methylphenyl bromide

N-phenyl-P,P-di(2-methylphenyl)phosphinic amide

(N-p-nitrophenyl)di-o-tolylphosphinic amide

di-o-tolylphosphine oxide

Downstream raw materials:

methyl di-o-tolylphosphinate

Bis(2-methylphenyl)(2-carbomethoxyphenyl)phosphinoxid

2-[bis-(2-bromomethyl-phenyl)-phosphinoyl]-benzoic acid methyl ester

2-(24-oxo-7,8,10,11,13,14,16,17,19,24-decahydro-5H-6,9,12,15,18-pentaoxa-24λ⁵-phospha-dibenzo[a,d]cycloeicosen-24-yl)-benzoic acid