2-Methylpropyl N-(2-chloropyridine-3-sulfonyl)-N-(3-Methoxy-5-Methylpyrazin-2-yl)carbaMate

Base Information

Chemical Name:2-Methylpropyl N-(2-chloropyridine-3-sulfonyl)-N-(3-Methoxy-5-Methylpyrazin-2-yl)carbaMate
CAS No.:186497-45-0
Molecular Formula:C16H19ClN4O5S
Molecular Weight:414.87
Hs Code.:
Mol file:186497-45-0.mol

Synonyms:isobutyl (2R)-2-(allyloxy)propanoate;Propanoic acid,2-(2-propenyloxy)-,2-methylpropyl ester,(2R);(2R)-(+)-isobutyl-2-(allyloxy)propanoate;isobutyl [(2-chloropyridin-3-yl)sulfonyl](3-methoxy-5-methylpyrazin-2-yl)carbamate;2-chloro-N-isobutoxycarbonyl-N-(3-methoxy-5-methylpyrazin-2-yl)-pyridine-3-sulphonamide;

Suppliers and Price of 2-Methylpropyl N-(2-chloropyridine-3-sulfonyl)-N-(3-Methoxy-5-Methylpyrazin-2-yl)carbaMate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 6 raw suppliers

Chemical Property of 2-Methylpropyl N-(2-chloropyridine-3-sulfonyl)-N-(3-Methoxy-5-Methylpyrazin-2-yl)carbaMate

Chemical Property:

PSA：119.96000
LogP:3.91070

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Methylpropyl N-(2-chloropyridine-3-sulfonyl)-N-(3-Methoxy-5-Methylpyrazin-2-yl)carbaMate

There total 1 articles about 2-Methylpropyl N-(2-chloropyridine-3-sulfonyl)-N-(3-Methoxy-5-Methylpyrazin-2-yl)carbaMate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 186497-47-2
isobutyl N-(3-methoxy-5-methylpyrazin-2-yl)-carbamate

: 6684-06-6
2-chloro-3-pyridinesulfonyl chloride

: 186497-45-0
2-chloro-N-isobutoxycarbonyl-N-(3-methoxy-5-methylpyrazin-2-yl)-pyridine-3-sulphonamide

Guidance literature:: With hydrogenchloride; In water;

Reference yield: 90.0%

: 186497-45-0
2-chloro-N-isobutoxycarbonyl-N-(3-methoxy-5-methylpyrazin-2-yl)-pyridine-3-sulphonamide

: 276694-22-5
[4-(1,3,4-oxadiazol-2-yl) phenyl]boronic acid

: N-(isobutoxycarbonyl) N-(3-methoxy-5-methylpyrazin-2-yl)-2-(4-[1,3,4-oxadiazol-2-yl]phenyl)pyridine-3-sulphonamide

Guidance literature:: With 4-methyl-morpholine; palladium diacetate; trisodium tris(3-sulfophenyl)phosphine; In water; isopropyl alcohol; toluene; at 60 - 80 ℃; for 5.08333h; Product distribution / selectivity;

Reference yield: 78.2%

: 186497-45-0
2-chloro-N-isobutoxycarbonyl-N-(3-methoxy-5-methylpyrazin-2-yl)-pyridine-3-sulphonamide

: 276694-22-5
[4-(1,3,4-oxadiazol-2-yl) phenyl]boronic acid

: N-(3-methoxy-5-methylpyrazin-2-yl)-2-(4-[1,3,4-oxadiazol-2-yl]phenyl)pyridine-3-sulphonamide sodium salt

Guidance literature:: 2-chloro-N-isobutoxycarbonyl-N-(3-methoxy-5-methylpyrazin-2-yl)-pyridine-3-sulphonamide; [4-(1,3,4-oxadiazol-2-yl) phenyl]boronic acid; With triethylamine; palladium diacetate; trisodium triphenylphosphine‐3,3′,3″‐trisulfonate; In ethanol; water; xylene; at 80 ℃; for 24h;

With sodium methylate; In methanol; ethanol; xylene; at 16 - 19 ℃; for 2h;