6684-06-6 Usage
Uses
Used in Pharmaceutical Industry:
2-Chloropyridine-3-sulfonyl chloride is used as a key intermediate in the synthesis of new drugs. Its reactivity allows for the introduction of the sulfonyl chloride group into pharmaceutical molecules, enhancing their biological activity and therapeutic potential.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Chloropyridine-3-sulfonyl chloride is utilized as a building block for the development of novel agrochemicals. Its ability to modify target molecules with the sulfonyl chloride group contributes to the creation of more effective and targeted pest control agents.
Used in Organic Synthesis:
2-Chloropyridine-3-sulfonyl chloride is employed as a versatile reagent in organic synthesis for the preparation of a wide range of chemical products. Its reactivity makes it a valuable intermediate in the production of fine chemicals for various industrial applications, including the synthesis of complex organic molecules and the modification of existing compounds to improve their properties.
Used in Research and Development:
In research settings, 2-Chloropyridine-3-sulfonyl chloride is used as a tool for exploring new chemical reactions and pathways. Its unique properties and reactivity enable scientists to investigate novel synthetic routes and develop innovative methods for the preparation of biologically active compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 6684-06-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,8 and 4 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6684-06:
(6*6)+(5*6)+(4*8)+(3*4)+(2*0)+(1*6)=116
116 % 10 = 6
So 6684-06-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H6ClNO2S/c1-5-6(11(7,9)10)3-2-4-8-5/h2-4H,1H3
6684-06-6Relevant academic research and scientific papers
Aqueous process chemistry: The preparation of aryl sulfonyl chlorides
Hogan, Philip J.,Cox, Brian G.
scheme or table, p. 875 - 879 (2010/04/22)
The use of aqueous acidic conditions for the preparation of arylsulfonyl chlorides from diazonium salts in the presence of copper salts, preferably CuCl, together with thionyl chloride as the sulfur dioxide source, has considerable advantages over recommended literature procedures, whereby reactions are carried out in acetic acid with minimisation of water content of the solvent. The method has been shown to be successful for a wide range of electron-deficient and electron-neutral aryl substrates. The sulfonyl chlorides are protected from hydrolysis by their low solubility in water, which results in their direct precipitation from the reaction mixture in good yields (>70%) and high strength (>98% w/w). The aqueous process, which is additionally safer and more robust, can be readily scaled up and has significant environmental benefits.