6684-06-6 Usage
General Description
2-Chloropyridine-3-sulfonyl chloride is a chemical compound with the molecular formula C5H3ClNOS. It is a sulfonyl chloride derivative of pyridine and is commonly used as a building block in organic synthesis. 2-Chloropyridine-3-sulfonyl chloride is a versatile reagent in the preparation of various pharmaceuticals, agrochemicals, and other biologically active compounds. It is known for its ability to introduce the sulfonyl chloride functional group into target molecules, and its reactivity makes it a valuable intermediate in the production of a wide range of chemical products. 2-Chloropyridine-3-sulfonyl chloride is used in the development of new drugs and in the production of fine chemicals for various industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 6684-06-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,8 and 4 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6684-06:
(6*6)+(5*6)+(4*8)+(3*4)+(2*0)+(1*6)=116
116 % 10 = 6
So 6684-06-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H6ClNO2S/c1-5-6(11(7,9)10)3-2-4-8-5/h2-4H,1H3
6684-06-6Relevant articles and documents
Aqueous process chemistry: The preparation of aryl sulfonyl chlorides
Hogan, Philip J.,Cox, Brian G.
scheme or table, p. 875 - 879 (2010/04/22)
The use of aqueous acidic conditions for the preparation of arylsulfonyl chlorides from diazonium salts in the presence of copper salts, preferably CuCl, together with thionyl chloride as the sulfur dioxide source, has considerable advantages over recommended literature procedures, whereby reactions are carried out in acetic acid with minimisation of water content of the solvent. The method has been shown to be successful for a wide range of electron-deficient and electron-neutral aryl substrates. The sulfonyl chlorides are protected from hydrolysis by their low solubility in water, which results in their direct precipitation from the reaction mixture in good yields (>70%) and high strength (>98% w/w). The aqueous process, which is additionally safer and more robust, can be readily scaled up and has significant environmental benefits.