Benzenemethanol, a-(cyclopropylmethyl)-

Base Information

• Chemical Name: Benzenemethanol, a-(cyclopropylmethyl)-
• CAS No.: 18729-51-6
• Molecular Formula: C11H14O
• Molecular Weight: 162.232
• Mol file: 18729-51-6.mol

Synonyms:cyclopropyl-2 phenyl-1 ethanol-1;2-cyclopropyl-1-phenylethan-1-ol;2-cyclopropyl-1-phenylethanol;

Chemical Property of Benzenemethanol, a-(cyclopropylmethyl)-

Chemical Property:

• Boiling Point: 267.1±9.0 °C(Predicted)
• PSA: 20.23000
• Density: 1.083±0.06 g/cm3(Predicted)
• LogP: 2.52010

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenemethanol, a-(cyclopropylmethyl)-

There total 11 articles about Benzenemethanol, a-(cyclopropylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

cyclopropylidene-2 acetophenone (80345-17-1) → 2-cyclopropyl-1-phenyl-1-ethanol (18729-51-6)

Guidance literature:

With sodium tetrahydroborate; In methanol;

DOI:10.1016/S0040-4039(01)81965-1

Reference yield: 62.0%

benzaldehyde (100-52-7) + chloro(cyclopropyl)methane (5911-08-0) → 2-cyclopropyl-1-phenyl-1-ethanol (18729-51-6)

Guidance literature:

With 4,4'-di-tert-butylbiphenyl; lithium; In tetrahydrofuran; at -78 ℃; for 1h;

DOI:10.1016/j.tetlet.2008.09.100

Reference yield:

1-Phenyl-2-(1-phenylsulfanyl-cyclopropyl)-ethanone (196602-62-7) → 2-cyclopropyl-1-phenylethanone (6739-22-6) + phenyl butyl ketone (1009-14-9) + 2-cyclopropyl-1-phenyl-1-ethanol (18729-51-6)

Guidance literature:

With Ra-Ni; In ethanol; 70 deg C, 4 h, rt, 20 h;

DOI:10.1016/S0040-4039(97)01546-3

upstream raw materials:

2-cyclopropyl-1-phenylethanone

cyclopropylmethyl iodide

benzaldehyde

cyclopropylidene-2 acetophenone

Downstream raw materials:

2-cyclopropyl-1,3-diphenyl-1,3-propanedione

2-cyclopropyl-1-phenylethanone