2-Propenoic acid, 3-phenyl-, 4-nitrophenyl ester

Base Information

• Chemical Name: 2-Propenoic acid, 3-phenyl-, 4-nitrophenyl ester
• CAS No.: 18736-43-1
• Molecular Formula: C15H11NO4
• Molecular Weight: 269.257
• Mol file: 18736-43-1.mol

Synonyms:

Chemical Property of 2-Propenoic acid, 3-phenyl-, 4-nitrophenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Propenoic acid, 3-phenyl-, 4-nitrophenyl ester

There total 9 articles about 2-Propenoic acid, 3-phenyl-, 4-nitrophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + cinnamoyl chloride (102-92-1,17082-09-6) → 4-nitro-phenyl cinnamate (18736-43-1)

Guidance literature:

With triethylamine; In tetrahydrofuran;

DOI:10.1016/j.tet.2020.131758

Reference yield: 78.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + Cinnamic acid (621-82-9) → 4-nitro-phenyl cinnamate (18736-43-1)

Guidance literature:

With silica gel-supported Preyssler acid; In toluene; at 110 ℃; for 7h;

DOI:10.1016/j.apcata.2009.11.037

Reference yield:

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + (E)-3-phenylacrylic acid (140-10-3) → 4-nitro-phenyl cinnamate (18736-43-1)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 - 25 ℃; for 2h;

DOI:10.1021/acs.orglett.9b04615

upstream raw materials:

4-nitro-phenol

cinnamoyl chloride

Cinnamic acid

p-nitrocinnamoyl p-nitro-phenyl ester

Downstream raw materials:

4-nitro-phenol

Cinnamic acid

C₁₃H₁₃NO₃

p-nitrocinnamoyl p-nitro-phenyl ester