Methanesulfonic acid, trifluoro-, 4-formyl-2,6-dimethylphenyl ester

Base Information

• Chemical Name: Methanesulfonic acid, trifluoro-, 4-formyl-2,6-dimethylphenyl ester
• CAS No.: 188112-49-4
• Molecular Formula: C10H9F3O4S
• Molecular Weight: 282.24
• Mol file: 188112-49-4.mol

Synonyms:3,5-dimethyl-4-trifluoromethanesulfonyloxybenzaldehyde;Methanesulfonic acid,trifluoro-,4-formyl-2,6-dimethylphenyl ester;trifluoro-methanesulfonic acid 4-formyl-2,6-dimethyl-phenyl ester;

Chemical Property of Methanesulfonic acid, trifluoro-, 4-formyl-2,6-dimethylphenyl ester

Chemical Property:

• PSA: 68.82000
• LogP: 3.42510

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methanesulfonic acid, trifluoro-, 4-formyl-2,6-dimethylphenyl ester

There total 5 articles about Methanesulfonic acid, trifluoro-, 4-formyl-2,6-dimethylphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

trifluoromethylsulfonic anhydride (358-23-6) + 4-hydroxy-3,5-dimethylbenzaldehyde (2233-18-3) → trifluoromethanesulfonic acid 4-formyl-2,6-dimethylphenyl ester (188112-49-4)

Guidance literature:

With pyridine; In dichloromethane; at 0 - 20 ℃; for 2h;

DOI:10.1021/jm401456d

Reference yield:

N,N-phenylbistrifluoromethane-sulfonimide (37595-74-7) + 4-(hydroxymethyl)-2,6-dimethylphenol (4397-14-2) → trifluoromethanesulfonic acid 4-formyl-2,6-dimethylphenyl ester (188112-49-4)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 20h; Inert atmosphere;

Reference yield:

4-hydroxy-3,5-dimethylbenzaldehyde (2233-18-3) + trifluoromethanesulfonic acid anhydride (1025373-45-8) → trifluoromethanesulfonic acid 4-formyl-2,6-dimethylphenyl ester (188112-49-4)

Guidance literature:

With pyridine; In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran;

upstream raw materials:

trifluoromethylsulfonic anhydride

4-hydroxy-3,5-dimethylbenzaldehyde

trifluoromethanesulfonic acid anhydride

N,N-phenylbistrifluoromethane-sulfonimide

Downstream raw materials:

2,6-dimethyl-4'-[[(1,1-dimethylethyl)diphenyl-silyl]oxy]-(1,1'-biphenyl)-4-carboxaldehyde

4-allyl-3,5-dimethyl-benzaldehyde

3-(4-formyl-2,6-dimethylphenyl)propenoic acid methyl ester

3-(2,6-dimethyl-4-(3-oxo-3-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propyl)phenyl)propanoic acid