Phenol, 4,4'-(2,2,2-trifluoro-1-phenylethylidene)bis-

Base Information

Chemical Name:Phenol, 4,4'-(2,2,2-trifluoro-1-phenylethylidene)bis-
CAS No.:1882-01-5
Molecular Formula:C20H15F3O2
Molecular Weight:344.333
Hs Code.:
DSSTox Substance ID:DTXSID50597298
Nikkaji Number:J846.332H
Wikidata:Q82492817

Synonyms:4,4'-(2,2,2-trifluoro-1-phenylethane-1,1-diyl)diphenol;1,1-bis(4-hydroxyphenyl)-1-phenyl-2,2,2-trifluoroethane;1882-01-5;SCHEMBL1171482;DTXSID50597298;Phenol, 4,4'-(2,2,2-trifluoro-1-phenylethylidene)bis-;1,1-bis(4-hydroxyphenyl)-l-phenyl-2,2,2-trifluoroethane;1,1-bis-(4-hydroxyphenyl)-1-phenyl-2,2,2-trifluoroethane;1,1-bis-(4-hydroxyphenyl)-l-phenyl-2,2,2-trifluoroethane

Suppliers and Price of Phenol, 4,4'-(2,2,2-trifluoro-1-phenylethylidene)bis-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Phenol, 4,4'-(2,2,2-trifluoro-1-phenylethylidene)bis-

Chemical Property:

XLogP3:5.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:344.10241420
Heavy Atom Count:25
Complexity:393

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C2=CC=C(C=C2)O)(C3=CC=C(C=C3)O)C(F)(F)F

Technology Process of Phenol, 4,4'-(2,2,2-trifluoro-1-phenylethylidene)bis-

There total 4 articles about Phenol, 4,4'-(2,2,2-trifluoro-1-phenylethylidene)bis- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 434-45-7
2,2,2-Trifluoroacetophenone

: 108-95-2,27073-41-2
phenol

: 1882-01-5
1,1-bis(4-hydroxyphenyl)-1-phenyl-2,2,2-trifluoroethane

Guidance literature:: With trifluorormethanesulfonic acid; at 45 ℃; Inert atmosphere;
DOI:10.1016/j.polymer.2015.12.006

Reference yield:

: 1,1-Bis-(4-methoxyphenyl)-1-phenyl-2,2,2-trifluoroethane

: 1882-01-5
1,1-bis(4-hydroxyphenyl)-1-phenyl-2,2,2-trifluoroethane

Guidance literature:: In acetic acid;

Reference yield:

: 6919-61-5
N-methoxy-N-methylbenzamide

: 1882-01-5
1,1-bis(4-hydroxyphenyl)-1-phenyl-2,2,2-trifluoroethane

Guidance literature:: Multi-step reaction with 2 steps

1.1: cesium fluoride / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere

2.1: trifluoromethylsulfonic anhydride / dichloromethane / 0.33 h / -78 °C / Inert atmosphere

2.2: 6 h / -78 - 20 °C / Inert atmosphere

With trifluoromethylsulfonic anhydride; cesium fluoride; In tetrahydrofuran; dichloromethane;
DOI:10.1021/acs.joc.7b02161