Benzene, [(1E)-2-cyclohexylethenyl]-

Base Information

• Chemical Name: Benzene, [(1E)-2-cyclohexylethenyl]-
• CAS No.: 18869-27-7
• Molecular Formula: C14H18
• Molecular Weight: 186.297
• Mol file: 18869-27-7.mol

Synonyms:

Chemical Property of Benzene, [(1E)-2-cyclohexylethenyl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzene, [(1E)-2-cyclohexylethenyl]-

There total 171 articles about Benzene, [(1E)-2-cyclohexylethenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 1-bromocyclohexane (108-85-0) → (E)-(2-cyclohexylvinyl)benzene (18869-27-7)

Guidance literature:

With copper; sodium carbonate; In N,N-dimethyl-formamide; at 79.84 ℃; for 12h; Catalytic behavior; Glovebox;

DOI:10.1039/c4cy01331j

Reference yield: 94.0%

1-(2-cyclohexylethynyl)benzene (33414-83-4) → (E)-(2-cyclohexylvinyl)benzene (18869-27-7)

Guidance literature:

With ethanol; Ru(η(2)-2-(2'-pyridyl)phenyl)Cl(CO)(PPh3)2; sodium t-butanolate; at 110 ℃; for 1h; stereoselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.organomet.0c00074

Reference yield: 93.0%

cyclohexane (110-82-7,25012-93-5) + (E)-3-phenylacrylic acid (140-10-3) → (E)-(2-cyclohexylvinyl)benzene (18869-27-7)

Guidance literature:

With di-tert-butyl peroxide; silver carbonate; at 110 ℃; for 12h; stereoselective reaction; Sealed tube; Inert atmosphere;

DOI:10.1039/c7ob02455j

upstream raw materials:

(+/-)-1-cyclohexyl-2-phenylethanol

oxalic acid

rac-2-cyclohexyl-1-phenylethan-1-ol

styrene

Downstream raw materials:

1,2-dibromo-1-cyclohexyl-2-phenyl-ethane

2-cyclohexyl-3-phenyl-oxirane

benzoic acid

Cyclohexanecarboxylic acid

Refernces

• 1、 Chen, Xiao-Yan,Yang, Shuang,Ren, Bao-Ping,Shi, Lei,Lin, Dong-Zi,Zhang, Hao,Liu, Hai-Yang. "Copper porphyrin-catalyzed cross dehydrogenative coupling of alkanes with carboxylic acids: Esterification and decarboxylation dual pathway". . . Retrieved 2021/08/13.
• 2、 Lu, Xiao-Yu,Gao, Ang,Liu, Qi-Le,Xia, Ze-Jie. "Photoinduced copper-catalyzed dual decarboxylative coupling of α,β-unsaturated carboxylic acids with redox-active esters". supporting information. . Retrieved 2021/06/15.