Dimethyl 2-(2-fluoro-4-nitrophenyl)malonate

Base Information

Chemical Name:Dimethyl 2-(2-fluoro-4-nitrophenyl)malonate
CAS No.:188975-47-5
Molecular Formula:C11H10FNO6
Molecular Weight:271.202
Hs Code.:2917399090
DSSTox Substance ID:DTXSID00700199
Wikidata:Q82631421
Mol file:188975-47-5.mol

Synonyms:188975-47-5;DIMETHYL 2-(2-FLUORO-4-NITROPHENYL)MALONATE;dimethyl 2-(2-fluoro-4-nitrophenyl)propanedioate;2-(Cyanomethylthio)aceticacid;SCHEMBL4405560;DTXSID00700199;MZYCNIFZHNVGKA-UHFFFAOYSA-N;AC5006;MFCD12198898;SY005905;Dimethyl (2-fluoro-4-nitrophenyl)malonate;CS-0449385;FT-0764425;Dimethyl (2-fluoro-4-nitrophenyl)propanedioate;DIMETHYL2-(2-FLUORO-4-NITROPHENYL)MALONATE;1,3-DIMETHYL 2-(2-FLUORO-4-NITROPHENYL)PROPANEDIOATE

Suppliers and Price of Dimethyl 2-(2-fluoro-4-nitrophenyl)malonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Dimethyl 2-(2-fluoro-4-nitrophenyl)malonate
5 g
$ 437.00

Crysdot
Dimethyl2-(2-Fluoro-4-nitrophenyl)malonate 95+%
10g
$ 306.00

Alichem
Dimethyl2-(2-Fluoro-4-nitrophenyl)malonate
10g
$ 400.00

AK Scientific
Dimethyl2-(2-fluoro-4-nitrophenyl)malonate
5g
$ 1072.00

Total 7 raw suppliers

Chemical Property of Dimethyl 2-(2-fluoro-4-nitrophenyl)malonate

Chemical Property:

PSA：98.42000
LogP:1.68670
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:271.04921520
Heavy Atom Count:19
Complexity:353

Purity/Quality:

97% ^*data from raw suppliers

Dimethyl 2-(2-fluoro-4-nitrophenyl)malonate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C(C1=C(C=C(C=C1)[N+](=O)[O-])F)C(=O)OC

Technology Process of Dimethyl 2-(2-fluoro-4-nitrophenyl)malonate

There total 2 articles about Dimethyl 2-(2-fluoro-4-nitrophenyl)malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 369-34-6
3,4-difluoronitrobenzene

: 108-59-8
malonic acid dimethyl ester

: 188975-47-5
dimethyl 2-(2-fluoro-4-nitrophenyl)malonate

Guidance literature:: malonic acid dimethyl ester; With sodium hydride; In dimethyl sulfoxide; at 100 ℃; for 0.666667h;

3,4-difluoronitrobenzene; In dimethyl sulfoxide; at 20 - 100 ℃; for 1.5h;

Reference yield: 73.0%

: 108-59-8
malonic acid dimethyl ester

: 185331-69-5
1-bromo-2-fluoro-4-nitrobenzene

: 188975-47-5
dimethyl 2-(2-fluoro-4-nitrophenyl)malonate

Guidance literature:: malonic acid dimethyl ester; 1-bromo-2-fluoro-4-nitrobenzene; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 70 ℃;

With water; ammonium chloride; In N,N-dimethyl-formamide; at 21 ℃;