Methanone, [(2R,3S)-3-(4-methylphenyl)oxiranyl]phenyl-

Base Information

Chemical Name:Methanone, [(2R,3S)-3-(4-methylphenyl)oxiranyl]phenyl-
CAS No.:189017-48-9
Molecular Formula:C16H14O2
Molecular Weight:238.286
Hs Code.:
DSSTox Substance ID:DTXSID90448891
Nikkaji Number:J1.585.973C
Wikidata:Q82268084

Synonyms:DTXSID90448891;Methanone, [(2R,3S)-3-(4-methylphenyl)oxiranyl]phenyl-;(2R,3S)-2-Benzoyl-3-p-tolyloxirane;Phenyl-(3-p-tolyl-oxiranyl)-methanone;189017-48-9

Suppliers and Price of Methanone, [(2R,3S)-3-(4-methylphenyl)oxiranyl]phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Methanone, [(2R,3S)-3-(4-methylphenyl)oxiranyl]phenyl-

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:238.099379685
Heavy Atom Count:18
Complexity:298

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2C(O2)C(=O)C3=CC=CC=C3
Isomeric SMILES:CC1=CC=C(C=C1)[C@H]2[C@@H](O2)C(=O)C3=CC=CC=C3

Technology Process of Methanone, [(2R,3S)-3-(4-methylphenyl)oxiranyl]phenyl-

There total 15 articles about Methanone, [(2R,3S)-3-(4-methylphenyl)oxiranyl]phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 4224-87-7
4-methyl-chalcone

: 189017-48-9
(2R,3S)-epoxy-3-(4-methylphenyl)-1-phenylpropan-1-one

Guidance literature:: With sodium hydroxide; C₅₅H₆₉F₁₂N₇O₂*ClH; dihydrogen peroxide; In water; toluene; at -10 ℃; for 4h; optical yield given as %ee; Inert atmosphere;
DOI:10.1055/s-0028-1087811

Reference yield: 93.0%

: 4224-87-7
4-methyl-chalcone

: 189017-48-9
(2R,3S)-epoxy-3-(4-methylphenyl)-1-phenylpropan-1-one

: 27729-96-0,32753-95-0,128134-36-1
[(2S,3R)-3-(4-methylphenyl)-2-oxiranyl]phenylmethanone

Guidance literature:: 4-methyl-chalcone; With tris(bis(trimethylsilyl)amido)lanthanum(III); (S,S)-N,N'-di(3,5-dimethylsalicylidene)-1,2-cyclohexanediamine; In acetonitrile; for 0.5h; Inert atmosphere;

With tert.-butylhydroperoxide; In acetonitrile; at -20 ℃; for 10h; Overall yield = 93 %; enantioselective reaction; Inert atmosphere;
DOI:10.1039/c9ra01529a

Reference yield: 85.0%

: 22252-14-8,72758-77-1,4224-87-7
(E)-3-(4-methylphenyl)-1-phenyl-2-propen-1-one

: 189017-48-9
(2R,3S)-epoxy-3-(4-methylphenyl)-1-phenylpropan-1-one

: 27729-96-0,32753-95-0,128134-36-1
[(2S,3R)-3-(4-methylphenyl)-2-oxiranyl]phenylmethanone

Guidance literature:: With poly-L-leucine; dihydrogen peroxide; ammonium bicarbonate; 336(R); In 1,2-dimethoxyethane; water; at 20 ℃; Title compound not separated from byproducts;
DOI:10.1081/SCC-120022166