7-Methyl-3-noradamantanol

Base Information

• Chemical Name: 7-Methyl-3-noradamantanol
• CAS No.: 1905-16-4
• Molecular Formula: C10H16O
• Molecular Weight: 152.236
• DSSTox Substance ID: DTXSID70397772
• Nikkaji Number: J1.468.191D
• Mol file: 1905-16-4.mol

Synonyms:1905-16-4;7-Methyl-3-noradamantanol;DTXSID70397772;6a-methylhexahydro-2,5-methanopentalen-3a(1H)-ol;SR-01000389480;SR-01000389480-1

Chemical Property of 7-Methyl-3-noradamantanol

Chemical Property:

• PSA: 20.23000
• LogP: 1.94750
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 152.120115130
• Heavy Atom Count: 11
• Complexity: 195

Purity/Quality:

7-Methyl-3-noradamantanol 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC12CC3CC(C1)CC2(C3)O

Technology Process of 7-Methyl-3-noradamantanol

There total 6 articles about 7-Methyl-3-noradamantanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

7-methylenebicyclo[3.3.1]nonan-3-one (17933-29-8) → 7-methyltricyclo[3.3.1.03,7]nonan-3-ol (1905-16-4) + 1-adamanthanol (768-95-6)

Guidance literature:

With methanol; N,N,N,N-tetraethylammonium tetrafluoroborate; In N,N-dimethyl-formamide; at 0 ℃; Electrolysis;

DOI:10.1246/bcsj.74.339

Reference yield:

1,3-dibromoadamantane (876-53-9) → 7-methyltricyclo[3.3.1.03,7]nonan-3-ol (1905-16-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / aqueous sodium hydroxide / dioxane / 18 h / 175 - 180 °C

2: 30 percent / tetraethylammonium tetrafluoroborate / dimethylformamide / 0 °C / Electrolysis

With sodium hydroxide; N,N,N,N-tetraethylammonium tetrafluoroborate; In 1,4-dioxane; N,N-dimethyl-formamide;

DOI:10.1246/bcsj.74.339

Reference yield:

7-methylenebicyclo[3.3.1]nonan-3-one (17933-29-8) → 7-methyltricyclo[3.3.1.03,7]nonan-3-ol (1905-16-4)

Guidance literature:

Multistep reaction; (i) Na, (ii) aq. HCl;

upstream raw materials:

7-methylenebicyclo[3.3.1]nonan-3-one

chloro-3 methyl-7 noradamantane

adamantane

1,3-dibromoadamantane