Methanone, (4-methoxyphenyl)[2-(trifluoromethyl)phenyl]-

Base Information

• Chemical Name: Methanone, (4-methoxyphenyl)[2-(trifluoromethyl)phenyl]-
• CAS No.: 190728-31-5
• Molecular Formula: C15H11F3O2
• Molecular Weight: 280.246
• Mol file: 190728-31-5.mol

Synonyms:(4-Methoxy-phenyl)-(2-trifluoromethyl-phenyl)-methanone;2-trifluoromethylphenyl 4-methoxyphenyl ketone;4-methoxy-2'-(trifluoromethyl)benzophenone;

Chemical Property of Methanone, (4-methoxyphenyl)[2-(trifluoromethyl)phenyl]-

Chemical Property:

• Boiling Point: 381.8±42.0 °C(Predicted)
• PSA: 26.30000
• Density: 1.245±0.06 g/cm3(Predicted)
• LogP: 3.94500

Purity/Quality:

95% ^*data from raw suppliers

4-Methoxy-2'-trifluoromethylbenzophenone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methanone, (4-methoxyphenyl)[2-(trifluoromethyl)phenyl]-

There total 3 articles about Methanone, (4-methoxyphenyl)[2-(trifluoromethyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

2-trifluoromethylbenzoyl chloride (312-94-7) → 2-Trifluoromethylphenyl 4-methoxyphenyl ketone (190728-31-5)

Guidance literature:

ytterbium(III) triflate; In nitromethane; methoxybenzene;

Reference yield: 50.0%

methoxybenzene (100-66-3) + 2-trifluoromethylbenzoyl chloride (312-94-7) → 2-Trifluoromethylphenyl 4-methoxyphenyl ketone (190728-31-5)

Guidance literature:

With ytterbium(III) triflate; In nitromethane; at 60 ℃; for 8h;

DOI:10.1016/j.bmc.2003.08.020

Reference yield:

→ 2-Trifluoromethylphenyl 4-methoxyphenyl ketone (190728-31-5)

Guidance literature:

upstream raw materials:

methoxybenzene

2-trifluoromethylbenzoyl chloride

Downstream raw materials:

2-trifluoromethylphenyl 4-hydroxyphenyl ketone

C₁₈H₁₅F₃O₂

C₁₈H₁₇F₃O₂

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