4-(1,3-Dioxolan-2-yl)aniline

Base Information

Chemical Name:4-(1,3-Dioxolan-2-yl)aniline
CAS No.:19073-14-4
Molecular Formula:C9H11NO2
Molecular Weight:165.192
Hs Code.:2932999099
DSSTox Substance ID:DTXSID60456105
Nikkaji Number:J2.547.531C
Wikidata:Q82278322
Mol file:19073-14-4.mol

Synonyms:4-(1,3-dioxolan-2-yl)aniline;19073-14-4;4-Aminobenzaldehyde ethylene acetal;4-[1,3]Dioxolan-2-yl-phenylamine;Benzenamine, 4-(1,3-dioxolan-2-yl)-;4-(1,3-dioxolan-2-yl)phenylamine;SCHEMBL698809;DTXSID60456105;AGTSXXZWXWHAKH-UHFFFAOYSA-N;2-(4-Aminophenyl)-1,3-dioxolane;MFCD00604220;AKOS006273104;AS-9586;CS-0180900;FT-0769955;A51126;A847852

Suppliers and Price of 4-(1,3-Dioxolan-2-yl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-(1,3-Dioxolan-2-yl)aniline
1 g
$ 376.00

Matrix Scientific
4-(1,3-Dioxolan-2-yl)aniline 97%
1g
$ 341.00

Crysdot
4-(1,3-Dioxolan-2-yl)aniline 95+%
250mg
$ 272.00

Crysdot
4-(1,3-Dioxolan-2-yl)aniline 95+%
1g
$ 620.00

American Custom Chemicals Corporation
4-(1,3-DIOXOLAN-2-YL)ANILINE 95.00%
5MG
$ 501.97

Acrotein
4-Aminobenzaldehydeethyleneacetal 97%
1g
$ 71.54

Total 16 raw suppliers

Chemical Property of 4-(1,3-Dioxolan-2-yl)aniline

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Melting Point:75-79 °C
Boiling Point:313.119oC at 760 mmHg
PKA:4.44±0.10(Predicted)
Flash Point:156.348oC
PSA：44.48000
Density:1.203g/cm3
LogP:1.89540
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:165.078978594
Heavy Atom Count:12
Complexity:138

Purity/Quality:

97% ^*data from raw suppliers

4-(1,3-Dioxolan-2-yl)aniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC(O1)C2=CC=C(C=C2)N
Uses 4-?(1,?3-?Dioxolan-?2-?yl)?aniline is a reagent used in the preparation of luminogens and fluorescent polyimides. Also used in the preparation of a novel class of small molecule caspase-3 inihibitors.

Technology Process of 4-(1,3-Dioxolan-2-yl)aniline

There total 7 articles about 4-(1,3-Dioxolan-2-yl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 2403-53-4
2-(4-nitrophenyl)-1,3-dioxolane

: 19073-14-4
4-(1,3-dioxolan-2-yl)aniline

Guidance literature:: With hydrogen; platinum(IV) oxide; In tetrahydrofuran;
DOI:10.1016/S0960-894X(01)00508-X

Reference yield: 95.6%

: 52161-21-4
N-[4-(1,3-dioxolan-2-yl)phenyl]acetamide

: 19073-14-4
4-(1,3-dioxolan-2-yl)aniline

Guidance literature:: With potassium hydroxide; In 1,4-dioxane; water; for 2.5h; Heating;

Reference yield:

: 555-16-8
4-nitrobenzaldehdye

: 19073-14-4
4-(1,3-dioxolan-2-yl)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / p-toluenesulfonic acid / benzene / 4.5 h / Heating

2: H₂; CH(OEt)3 / PtO₂ / tetrahydrofuran / 1.5 h / 5320.36 Torr

With hydrogen; toluene-4-sulfonic acid; orthoformic acid triethyl ester; platinum(IV) oxide; In tetrahydrofuran; benzene;
DOI:10.1002/chem.200601682