2-(5-BroMo-pyridin-3-yloxyMethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

Base Information

Chemical Name:2-(5-BroMo-pyridin-3-yloxyMethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester
CAS No.:191162-30-8
Molecular Formula:C15H21BrN2O3
Molecular Weight:357.247
Hs Code.:
Mol file:191162-30-8.mol

Synonyms:(S)-3-(5-bromo-pyridin-3-yloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester;3-bromo-5-[[1-(tert-butoxycarbonyl)-2(S)-pyrrolidinyl]methoxy]pyridine;(S)-2-(5-Bromo-pyridin-3-yloxymethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester;5-bromo-3-(1-tert-butoxycarbonyl-2(S)-pyrrolidinylmethoxy)pyridine;5-bromo-3-(1-BOC-2-(S)-pyrrolidinylmethoxy)pyridine;(S)-1-(tert-butoxycarbonyl)-2-(5-bromo-3-pyridinyloxymethyl)pyrrolidine;

Suppliers and Price of 2-(5-BroMo-pyridin-3-yloxyMethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-(5-BroMo-pyridin-3-yloxyMethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

Chemical Property:

PSA：51.66000
LogP:3.56030

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(5-BroMo-pyridin-3-yloxyMethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

There total 2 articles about 2-(5-BroMo-pyridin-3-yloxyMethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 74115-13-2
5-bromopyridine-3-ol

: 69610-40-8
N-(tert-butoxycarbonyl)-L-prolinol

: 191162-30-8
(S)-2-((5-bromopyridin-3-yloxy)methyl)pyrrolidine-1-carboxylic acid tert-butyl ester

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 0 - 20 ℃;

Reference yield:

: 191162-30-8
(S)-2-((5-bromopyridin-3-yloxy)methyl)pyrrolidine-1-carboxylic acid tert-butyl ester

Guidance literature:

Reference yield: 100.0%

: 191162-30-8
(S)-2-((5-bromopyridin-3-yloxy)methyl)pyrrolidine-1-carboxylic acid tert-butyl ester

: 1441118-55-3
4-[2-[4-(trifluoromethyl)benzyloxy]ethyl]piperidine

: 3-[[1-(tert-butoxycarbonyl)-2(S)-pyrrolidinyl]methoxy]-5-[4-[2-[4-(trifluoromethyl)benzyloxy]ethyl]-1-piperidinyl]pyridine

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium t-butanolate; In toluene; at 98 - 100 ℃; for 4h; Inert atmosphere;