D-Tryptophan, N-((4-(2-phenyl-2H-tetrazol-5-yl)phenyl)sulfonyl)-

Base Information

Chemical Name:D-Tryptophan, N-((4-(2-phenyl-2H-tetrazol-5-yl)phenyl)sulfonyl)-
CAS No.:193809-84-6
Molecular Formula:C24H20N6O4S
Molecular Weight:
Hs Code.:
UNII:CDL03A411T
DSSTox Substance ID:DTXSID40432109
Nikkaji Number:J2.132.802B
Wikidata:Q27275416
Pharos Ligand ID:L2KR1QS3MUGB
ChEMBL ID:CHEMBL345597
Mol file:193809-84-6.mol

Synonyms:MMI 166;MMI-166;MMI166;N-alpha-(4-(2-phenyl-2H- tetrazole-5-yl) phenyl sulfonyl)-D-tryptophan

Suppliers and Price of D-Tryptophan, N-((4-(2-phenyl-2H-tetrazol-5-yl)phenyl)sulfonyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of D-Tryptophan, N-((4-(2-phenyl-2H-tetrazol-5-yl)phenyl)sulfonyl)-

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:8
Exact Mass:488.12667431
Heavy Atom Count:35
Complexity:824

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)N2N=C(N=N2)C3=CC=C(C=C3)S(=O)(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)O
Isomeric SMILES:C1=CC=C(C=C1)N2N=C(N=N2)C3=CC=C(C=C3)S(=O)(=O)N[C@H](CC4=CNC5=CC=CC=C54)C(=O)O

Technology Process of D-Tryptophan, N-((4-(2-phenyl-2H-tetrazol-5-yl)phenyl)sulfonyl)-

There total 5 articles about D-Tryptophan, N-((4-(2-phenyl-2H-tetrazol-5-yl)phenyl)sulfonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 203640-02-2
(R)-3-(1H-Indol-3-yl)-2-[4-(2-phenyl-2H-tetrazol-5-yl)-benzenesulfonylamino]-propionic acid benzyl ester

: 193809-84-6
(R)-3-(1H-Indol-3-yl)-2-[4-(2-phenyl-2H-tetrazol-5-yl)-benzenesulfonylamino]-propionic acid

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; ethyl acetate;
DOI:10.1021/jm9707582

Reference yield:

: 99504-75-3
5-(4-bromophenyl)-2-phenyl-2H-tetrazole

: 193809-84-6
(R)-3-(1H-Indol-3-yl)-2-[4-(2-phenyl-2H-tetrazol-5-yl)-benzenesulfonylamino]-propionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) n-BuLi, 2.) SO₂, 3.) SO₂Cl₂

2: N-methylmorpholine / CH₂Cl₂ / Ambient temperature

3: H₂ / 10percent Pd/C / methanol; ethyl acetate

With 4-methyl-morpholine; n-butyllithium; sulfuryl dichloride; sulfur dioxide; hydrogen; palladium on activated charcoal; In methanol; dichloromethane; ethyl acetate;
DOI:10.1021/jm9707582

Reference yield:

: 126090-33-3
(R)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionic acid benzyl ester

: 193809-84-6
(R)-3-(1H-Indol-3-yl)-2-[4-(2-phenyl-2H-tetrazol-5-yl)-benzenesulfonylamino]-propionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: CH₂Cl₂ / 1 h / Ambient temperature

2: N-methylmorpholine / CH₂Cl₂ / Ambient temperature

3: H₂ / 10percent Pd/C / methanol; ethyl acetate

With 4-methyl-morpholine; hydrogen; palladium on activated charcoal; In methanol; dichloromethane; ethyl acetate;
DOI:10.1021/jm9707582