D-Alanine, D-alanyl-L-lysyl-3-cyclohexyl-L-alanyl-L-valyl-L-alanyl-L-alanyl-L-tryptophyl-L- threonyl-L-leucyl-L-lysyl-L-alanyl-L-alanyl-

Base Information

• Chemical Name: D-Alanine, D-alanyl-L-lysyl-3-cyclohexyl-L-alanyl-L-valyl-L-alanyl-L-alanyl-L-tryptophyl-L- threonyl-L-leucyl-L-lysyl-L-alanyl-L-alanyl-
• CAS No.: 194039-57-1
• Molecular Formula: C₆₅H₁₀₈N₁₆O₁₅
• Molecular Weight: 1353.67
• Mol file: 194039-57-1.mol

Synonyms:

Chemical Property of D-Alanine, D-alanyl-L-lysyl-3-cyclohexyl-L-alanyl-L-valyl-L-alanyl-L-alanyl-L-tryptophyl-L- threonyl-L-leucyl-L-lysyl-L-alanyl-L-alanyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of D-Alanine, D-alanyl-L-lysyl-3-cyclohexyl-L-alanyl-L-valyl-L-alanyl-L-alanyl-L-tryptophyl-L- threonyl-L-leucyl-L-lysyl-L-alanyl-L-alanyl-

There total 1 articles about D-Alanine, D-alanyl-L-lysyl-3-cyclohexyl-L-alanyl-L-valyl-L-alanyl-L-alanyl-L-tryptophyl-L- threonyl-L-leucyl-L-lysyl-L-alanyl-L-alanyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Fmoc-Val-OH (68858-20-8) + Fmoc-Leu-OH (35661-60-0) + N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine (35661-39-3,136132-75-7) + Fmoc-Lys(tert-butoxycarbonyl) (71989-26-9) + Fmoc-Thr(tBu)-OH (71989-35-0,138797-71-4) + N-(9-fluorenylmethoxycarbonyl)-D-alanine (35661-38-2,35661-39-3,79990-15-1,136132-75-7) + 3-[(S)-2-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]indole-1-carboxylic acid tert-butyl ester (143824-78-6,163619-04-3) + FMOC-D-Cha-OH → aKXAAWTLKA (194039-57-1)

Guidance literature:

N-(9-fluorenylmethoxycarbonyl)-D-alanine; With 1-methyl-1H-imidazole; tentagel HMBA resin; 1-(mesitylene-2-sulfonyl)-3-nitro-1H-1,2,4-triazole; In dichloromethane; for 1h; Inert atmosphere; solid phase reaction;

With piperazine; In N,N-dimethyl-formamide; Microwave irradiation; solid phase reaction;

Fmoc-Val-OH; Fmoc-Leu-OH; N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine; Fmoc-Lys(tert-butoxycarbonyl); Fmoc-Thr(tBu)-OH; 3-[(S)-2-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]indole-1-carboxylic acid tert-butyl ester; FMOC-D-Cha-OH; Further stages;

DOI:10.1021/ja1083915

upstream raw materials:

Fmoc-Val-OH

Fmoc-Leu-OH

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

Fmoc-Lys(tert-butoxycarbonyl)