2-METHYL-5-BENZYLOXYANILIN

Base Information

• Chemical Name: 2-METHYL-5-BENZYLOXYANILIN
• CAS No.: 19499-88-8
• Molecular Formula: C14H15NO
• Molecular Weight: 213.279
• Hs Code.: 2922199090
• Mol file: 19499-88-8.mol

Synonyms:5-Benzyloxy-2-methylphenylamine;2-Methyl-5-benzyloxyanilin;2-Amino-4-benzyloxy-toluol;

Chemical Property of 2-METHYL-5-BENZYLOXYANILIN

Chemical Property:

• PSA: 35.25000
• LogP: 3.73740
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

99%, ^*data from raw suppliers

5-Benzyloxy-2-methyl-phenylamine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-METHYL-5-BENZYLOXYANILIN

There total 3 articles about 2-METHYL-5-BENZYLOXYANILIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

4-(benzyloxy)-1-methyl-2-nitrobenzene (24239-67-6) → 5-(benzyloxy)-2-methylaniline (19499-88-8)

Guidance literature:

With hydrogen; In methanol; at 20 ℃; for 16h;

Reference yield:

benzyl bromide (100-39-0) → 5-(benzyloxy)-2-methylaniline (19499-88-8)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C

2: hydrogen / methanol / 16 h / 20 °C

With hydrogen; potassium carbonate; In methanol; N,N-dimethyl-formamide;

Reference yield:

4-methyl-5-nitrophenol (2042-14-0) → 5-(benzyloxy)-2-methylaniline (19499-88-8)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C

2: hydrogen / methanol / 16 h / 20 °C

With hydrogen; potassium carbonate; In methanol; N,N-dimethyl-formamide;

upstream raw materials:

4-(benzyloxy)-1-methyl-2-nitrobenzene

benzyl bromide

4-methyl-5-nitrophenol

Downstream raw materials:

N-(5-Benzyloxy-2-methyl-phenyl)-amino-acetaldehyd-diaethylacetal

4-benzyloxy-2-iodo-1-methylbenzene