3,3-Bis(4-chlorophenyl)prop-2-enoic acid

Base Information

• Chemical Name: 3,3-Bis(4-chlorophenyl)prop-2-enoic acid
• CAS No.: 19618-36-1
• Molecular Formula: C15H10Cl2O2
• Molecular Weight: 293.149
• DSSTox Substance ID: DTXSID40494747
• Mol file: 19618-36-1.mol

Synonyms:3,3-Bis(4-chlorophenyl)prop-2-enoic acid;19618-36-1;SCHEMBL8937433;DTXSID40494747;SACMDWWKRKJTOL-UHFFFAOYSA-N;3,3-Bis(p-chlorophenyl)acrylic acid

Chemical Property of 3,3-Bis(4-chlorophenyl)prop-2-enoic acid

Chemical Property:

• XLogP3: 5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 292.0057849
• Heavy Atom Count: 19
• Complexity: 314

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1C(=CC(=O)O)C2=CC=C(C=C2)Cl)Cl

Technology Process of 3,3-Bis(4-chlorophenyl)prop-2-enoic acid

There total 19 articles about 3,3-Bis(4-chlorophenyl)prop-2-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

ethyl 3,3-bis(4'-chlorophenyl)prop-2-enoate (95269-22-0,133262-95-0) → 3,3-bis(4-chlorophenyl)acrylic acid (19618-36-1)

Guidance literature:

With potassium hydroxide; In ethanol;

Reference yield: 83.0%

3,3-bis(4-chlorophenyl)acrylaldehyde (23594-02-7) → 3,3-bis(4-chlorophenyl)acrylic acid (19618-36-1)

Guidance literature:

With sodium chlorite; sodium dihydrogenphosphate dihydrate; In water; dimethyl sulfoxide; at 20 ℃; for 9h;

DOI:10.1002/ejoc.201600193

Reference yield:

methyl 3,3-bis(4-chlorophenyl)acrylate (101423-67-0) → 3,3-bis(4-chlorophenyl)acrylic acid (19618-36-1)

Guidance literature:

With sodium hydroxide; In methanol; water; at 50 ℃; for 6h; Sealed tube;

DOI:10.1039/c9cc10080f

upstream raw materials:

oxalyl dichloride

1,1-bis(p-chlorophenyl)ethene

4,4'-(2-bromoethene-1,1-diyl)bis(chlorobenzene)

1,1-dichloro-3,3-bis-(4-chloro-phenyl)-allene

Downstream raw materials:

1,1-bis(4-chlorophenyl)ethane

3,3-bis-(4-chloro-phenyl)-propionic acid

4-[3,3-bis-(4-chloro-phenyl)-acryloyl]-morpholine

3.3-Bis-(4-chlor-phenyl)-acrylsaeure-amid