2-Methoxy-2-phenyl-1,3-dioxolane

Base Information

• Chemical Name: 2-Methoxy-2-phenyl-1,3-dioxolane
• CAS No.: 19798-73-3
• Molecular Formula: C10H12O3
• Molecular Weight: 180.203
• DSSTox Substance ID: DTXSID30490011
• Nikkaji Number: J1.454.539E
• Wikidata: Q82333584
• Mol file: 19798-73-3.mol

Synonyms:2-methoxy-2-phenyl-1,3-dioxolane;19798-73-3;SCHEMBL6547330;DTXSID30490011;2-phenyl-2-methoxy-1,3-dioxolane

Chemical Property of 2-Methoxy-2-phenyl-1,3-dioxolane

Chemical Property:

• XLogP3: 1.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 180.078644241
• Heavy Atom Count: 13
• Complexity: 158

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1(OCCO1)C2=CC=CC=C2

Technology Process of 2-Methoxy-2-phenyl-1,3-dioxolane

There total 2 articles about 2-Methoxy-2-phenyl-1,3-dioxolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethylene glycol (107-21-1) + orthobenzoic acid trimethyl ester (707-07-3) → 2-phenyl-2-methoxy-1,3-dioxolane (19798-73-3)

Guidance literature:

With toluene-4-sulfonic acid; at 150 ℃;

Reference yield:

→ 2-phenyl-2-methoxy-1,3-dioxolane (19798-73-3)

Guidance literature:

aus Aethylenglykol, Orthobenzoesaeuremethylester in Ggw. v. p-Toluolsulfonsaeure;

Reference yield: 88.0%

1-styrenyloxytrimethylsilane (13735-81-4) + 2-phenyl-2-methoxy-1,3-dioxolane (19798-73-3) → 1-phenyl-2-(2-phenyl-1,3-dioxolan-2-yl)-ethan-1-one (55337-53-6)

Guidance literature:

With zinc chloride diethyl ether; In dichloromethane; for 1h; Ambient temperature;

DOI:10.1007/BF00799167

upstream raw materials:

ethylene glycol

orthobenzoic acid trimethyl ester

Downstream raw materials:

2-(tert-butylperoxy)-2-phenyl-1,3-dioxolane

(1-methyl-1-phenyl-ethyl)-(2-phenyl-[1,3]dioxolan-2-yl)-peroxide

2-phenyl-[1,3]dioxolan-2-yl hydroperoxide

2-methoxyethyl benzoate