4-[2-(Pyrrolidin-1-yl)ethyl]pyridine

Base Information

• Chemical Name: 4-[2-(Pyrrolidin-1-yl)ethyl]pyridine
• CAS No.: 67580-65-8
• Molecular Formula: C11H16N2
• Molecular Weight: 176.261
• Hs Code.: 2933990090
• European Community (EC) Number: 654-625-4
• NSC Number: 42776
• UNII: YGK7RN9FSZ
• DSSTox Substance ID: DTXSID30285782
• Wikidata: Q82021282
• ChEMBL ID: CHEMBL405070
• Mol file: 67580-65-8.mol

Synonyms:67580-65-8;4-[2-(pyrrolidin-1-yl)ethyl]pyridine;4-(2-Tetrahydro-1H-pyrrol-1-ylethyl)pyridine;4-(2-pyrrolidin-1-ylethyl)pyridine;4-(2-(pyrrolidin-1-yl)ethyl)pyridine;MLS000737070;CHEMBL405070;NSC-42776;NSC42776;YGK7RN9FSZ;SCHEMBL3993201;DTXSID30285782;HMS2752A23;BDBM50372345;STL324986;4-[2-(1-pyrrolidinyl)ethyl]pyridine;AKOS006227946;4-(2-PYRROLIDINOETHYL)PYRIDINE;PD181599;SMR000038089;Pyridine, 4-[2-(1-pyrrolidinyl)ethyl]-;CS-0366221;FT-0616561;Z53116267

Chemical Property of 4-[2-(Pyrrolidin-1-yl)ethyl]pyridine

Chemical Property:

• Vapor Pressure: 0.00453mmHg at 25°C
• Boiling Point: 120-124ºC 4mm
• Flash Point: 121.6ºC
• PSA: 16.13000
• Density: 1.029g/cm3
• LogP: 1.65780
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 176.131348519
• Heavy Atom Count: 13
• Complexity: 135

Purity/Quality:

98%min ^*data from raw suppliers

4-(2-tetrahydro-1H-pyrrol-1-ylethyl)pyridine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(C1)CCC2=CC=NC=C2

Technology Process of 4-[2-(Pyrrolidin-1-yl)ethyl]pyridine

There total 1 articles about 4-[2-(Pyrrolidin-1-yl)ethyl]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

pyrrolidine (123-75-1) + 4-vinylpyridine (100-43-6,329041-72-7) → 4-(2-pyrrolidin-1-yl-ethyl)-pyridine (67580-65-8)

Guidance literature:

With NPs-Fe₃O₄-DE-bmim3PW; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/j.tetlet.2016.01.107

Reference yield:

4-(2-pyrrolidin-1-yl-ethyl)-pyridine (67580-65-8) → 4-(2-(pyrrolidin-1-yl)ethyl)piperidine (14759-08-1)

Guidance literature:

With acetic acid; platinum; under 2942.03 Torr; Hydrogenation;

upstream raw materials:

pyrrolidine

4-vinylpyridine

Downstream raw materials:

4-(2-(pyrrolidin-1-yl)ethyl)piperidine

Refernces