2-Formylphenyl 4-methylbenzenesulfonate

Base Information

• Chemical Name: 2-Formylphenyl 4-methylbenzenesulfonate
• CAS No.: 19820-56-5
• Molecular Formula: C14H12O4S
• Molecular Weight: 276.313
• DSSTox Substance ID: DTXSID501250374
• Nikkaji Number: J920.880A
• Mol file: 19820-56-5.mol

Synonyms:2-formylphenyl 4-methylbenzenesulfonate;19820-56-5;(2-formylphenyl) 4-methylbenzenesulfonate;2-formylphenyl 4-methylbenzene-1-sulfonate;2-tosyloxybenzaldehyde;2-(Tosyloxy)benzaldehyde;UPCMLD00WMAL369;SCHEMBL1200310;DTXSID501250374;BBL023805;MFCD00431696;STK500952;2-formylphenyl4-methylbenzenesulfonate;AKOS000294793;VS-07518;CS-0318339;2-formyl-1-(4-methylphenylsulfonyloxy)benzene;2-[[(4-Methylphenyl)sulfonyl]oxy]benzaldehyde;A919454;SR-01000078297;SR-01000078297-1

Chemical Property of 2-Formylphenyl 4-methylbenzenesulfonate

Chemical Property:

• Melting Point: 61.8 °C (ethanol)
• PSA: 68.82000
• LogP: 3.65600
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 276.04563003
• Heavy Atom Count: 19
• Complexity: 390

Purity/Quality:

97% ^*data from raw suppliers

2-Formylphenyl 4-methylbenzenesulfonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)OC2=CC=CC=C2C=O

Technology Process of 2-Formylphenyl 4-methylbenzenesulfonate

There total 6 articles about 2-Formylphenyl 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

salicylaldehyde (90-02-8) + p-toluenesulfonyl chloride (98-59-9) → 2-formylphenyl tosylate (19820-56-5)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/ic901938e

Reference yield: 71.0%

2-methyl-benzyl alcohol (89-95-2) + p-toluenesulfonyl chloride (98-59-9) → 2-formylphenyl tosylate (19820-56-5)

Guidance literature:

With sodium hydroxide; In dichloromethane; water; at 20 ℃;

DOI:10.1016/S0040-4039(00)01746-9

Reference yield:

salicylaldehyde, thallium(I) salt (89290-01-7) + p-toluenesulfonyl chloride (98-59-9) → 2-formylphenyl tosylate (19820-56-5)

Guidance literature:

In N,N-dimethyl-formamide;

DOI:10.1021/ja01011a040

upstream raw materials:

salicylaldehyde

p-toluenesulfonyl chloride

salicylaldehyde, thallium(I) salt

toluene-4-sulfonic acid phenyl ester

Downstream raw materials:

C₅₄H₅₆N₄O₆S₂

2'-methylbiphenyl-2-carboxaldehyde

2-(cyano-N,N-dimethylamino)methylphenyl tosylate

1,4-diphenylpyrazole-5-(2-hydroxyphenyl)pyrazole