4(1H)-Pyridinone, 3,5-dinitro-

Base Information

• Chemical Name: 4(1H)-Pyridinone, 3,5-dinitro-
• CAS No.: 19872-96-9
• Molecular Formula: C₅H₃N₃O₅
• Molecular Weight: 185.096
• Mol file: 19872-96-9.mol

Synonyms:3,5-Dinitro-1H-pyridin-4-one;3.5-dinitro-1H-pyridin-4-one;3,5-dinitro-4(1H)-pyridinone;3,5-dinitro-4-pyridone;3,5-dinitropyridin-4(1H)-one;

Chemical Property of 4(1H)-Pyridinone, 3,5-dinitro-

Chemical Property:

• PSA: 124.50000
• LogP: 1.23770

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4(1H)-Pyridinone, 3,5-dinitro-

There total 1 articles about 4(1H)-Pyridinone, 3,5-dinitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-pyridone (108-96-3,26266-70-6) → 3-nitro-4(1H)-pyridinone (15590-90-6) + 1H-3,5-dinitropyridine-4-one (19872-96-9)

Guidance literature:

With sulfuric acid; nitric acid;

DOI:10.3987/COM-05-10491

Reference yield:

1H-3,5-dinitropyridine-4-one (19872-96-9) → BF4(1-)*C42H41N6O2(1+)

Guidance literature:

Multi-step reaction with 5 steps

1: thionyl chloride; N,N-dimethyl-formamide / 16 h / Reflux; Inert atmosphere

2: N-ethyl-N,N-diisopropylamine / 1,4-dioxane / 24 h / 20 °C / Inert atmosphere

3: palladium 10% on activated carbon; hydrogen; potassium carbonate / ethanol / 48 h

4: pyridine / 6 h / 0 - 20 °C / Inert atmosphere

5: acetonitrile / 20 °C

With pyridine; thionyl chloride; palladium 10% on activated carbon; hydrogen; potassium carbonate; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; In 1,4-dioxane; ethanol; acetonitrile;

DOI:10.1021/ol1029589

Reference yield:

1H-3,5-dinitropyridine-4-one (19872-96-9) → BF4(1-)*C30H41N6(1+)

Guidance literature:

Multi-step reaction with 5 steps

1: thionyl chloride; N,N-dimethyl-formamide / 16 h / Reflux; Inert atmosphere

2: N-ethyl-N,N-diisopropylamine / 1,4-dioxane / 24 h / 20 °C / Inert atmosphere

3: palladium 10% on activated carbon; hydrogen; potassium carbonate / ethanol / 48 h

4: sodium cyanoborohydride / methanol; water / 0 - 20 °C / Inert atmosphere

5: acetonitrile / 20 °C

With thionyl chloride; palladium 10% on activated carbon; hydrogen; sodium cyanoborohydride; potassium carbonate; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; In 1,4-dioxane; methanol; ethanol; water; acetonitrile;

DOI:10.1021/ol1029589

upstream raw materials:

4-pyridone

Downstream raw materials:

4-chloro-3,5-dinitropyridine

(3,5-dinitropyridin-4-yl)methylamine

1,6-dibenzyl-2,3,5,6-tetrahydro-1H,4H-1,3a,6,8-tetraazaphenalene