2,5,6-Triamino-4-Benzyloxypyrimidine

Base Information

• Chemical Name: 2,5,6-Triamino-4-Benzyloxypyrimidine
• CAS No.: 19916-72-4
• Molecular Formula: C11H13N5O
• Molecular Weight: 231.257
• DSSTox Substance ID: DTXSID20431195
• Nikkaji Number: J634.539E
• ChEMBL ID: CHEMBL334187
• Mol file: 19916-72-4.mol

Synonyms:2,5,6-Triamino-4-Benzyloxypyrimidine;19916-72-4;CHEMBL334187;SCHEMBL3338311;DTXSID20431195;QGOLEGLENLEGAL-UHFFFAOYSA-N;2,4,5-triamino-6-benzyloxypyrimidine;6-Benzyloxypyrimidine-2,4,5-triamine;2,4,5-triamino-6-benzyloxy-pyrimidine

Chemical Property of 2,5,6-Triamino-4-Benzyloxypyrimidine

Chemical Property:

• PSA: 113.80000
• LogP: 1.89470
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 231.11201006
• Heavy Atom Count: 17
• Complexity: 234

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COC2=NC(=NC(=C2N)N)N

Technology Process of 2,5,6-Triamino-4-Benzyloxypyrimidine

There total 3 articles about 2,5,6-Triamino-4-Benzyloxypyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

(E)-6-(benzyloxy)-5-((4-chlorophenyl)diazenyl)pyrimidine-2,4-diamine → 2,4,5-triamino-6-benzyloxy-pyrimidine (19916-72-4)

Guidance literature:

With acetic acid; zinc; In ethanol; at 70 ℃; for 2h; Inert atmosphere;

DOI:10.1039/c7md00268h

Reference yield: 35.0%

2,4-diamino-6-(benzyloxy)-5-nitrosopyrimidine (101724-61-2) → 2,4,5-triamino-6-benzyloxy-pyrimidine (19916-72-4)

Guidance literature:

2,4-diamino-6-(benzyloxy)-5-nitrosopyrimidine; With sodium dithionite; water; at 20 - 50 ℃;

With ammonia; In water; pH=7;

Reference yield:

→ 2,4,5-triamino-6-benzyloxy-pyrimidine (19916-72-4)

Guidance literature:

5-Nitroso-2,4-diamino-6-benzyloxy-pyrimidin, Reduktion mit wss. Na-dithionit-Lsg., 50gradC;

upstream raw materials:

2,4-diamino-6-(benzyloxy)-5-nitrosopyrimidine

Downstream raw materials:

7-(benzyloxy)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine

2-amino-4-(benzyloxy)-6-phenylpteridin-7(8H)-one

2-(8-aza-O⁶-benzylguan-9-yl)ethyl-β-D-tetra-O-acetylglucoside

2-amino-O⁴-benzyl-6-formylpteridine