1-(4-Fluorobenzyl)piperazine dihydrochloride

Base Information

Chemical Name:1-(4-Fluorobenzyl)piperazine dihydrochloride
CAS No.:199672-06-5
Molecular Formula:C11H15FN2.2ClH
Molecular Weight:267.17000
Hs Code.:2933599090
UNII:YZ8YLK7R9F
DSSTox Substance ID:DTXSID80506676
Mol file:199672-06-5.mol

Synonyms:199672-06-5;1-(4-fluorobenzyl)piperazine dihydrochloride;1-(4-Fluoro-benzyl)-piperazine 2HCl;p-Fluoro bzp hydrochloride;YZ8YLK7R9F;4-Fluoro bzp hydrochloride;Para-fluoro bzp hydrochloride;4-Fluoro BZP (dihydrochloride);1-(4-fluorobenzyl)piperazine 2HCl;1-[(4-fluorophenyl)methyl]piperazine;dihydrochloride;1-(p-Fluorobenzyl)piperazine hydrochloride;1-(4-Fluorobenzyl)piperazine hydrochloride;1-(Para-fluorobenzyl)piperazine hydrochloride;Piperazine, 1-((4-fluorophenyl)methyl)-, dihydrochloride;Piperazine, 1-((4-fluorophenyl)methyl)-, hydrochloride (1:2);1-(4-FLUORO-BENZYL)-PIPERAZINE DIHYDROCHLORIDE;UNII-YZ8YLK7R9F;SCHEMBL3062972;?4-fluoro BZP (hydrochloride);DTXSID80506676;LEYGHHPTNYWQEF-UHFFFAOYSA-N;AKOS024462819;AB90923;N-(4-fluorobenzyl) piperazine dihydrochloride;A837029;EN300-12326784;1-[(4-FLUOROPHENYL)METHYL]PIPERAZINE DIHYDROCHLORIDE;1-[(4-Fluorophenyl)methyl]piperazine--hydrogen chloride (1/2)

Suppliers and Price of 1-(4-Fluorobenzyl)piperazine dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
4-fluoro BZP (hydrochloride) ≥98%
100mg
$ 144.00

Cayman Chemical
4-fluoro BZP (hydrochloride) ≥98%
50mg
$ 81.00

Cayman Chemical
4-fluoro BZP (hydrochloride) ≥98%
10mg
$ 35.00

American Custom Chemicals Corporation
1-(4-FLUORO-BENZYL)-PIPERAZINE HYDROCHLORIDE 95.00%
5G
$ 1298.86

AK Scientific
1-(4-Fluorobenzyl)piperazinedihydrochloride
100mg
$ 294.00

AK Scientific
1-(4-Fluorobenzyl)piperazinedihydrochloride
10mg
$ 147.00

Total 23 raw suppliers

Chemical Property of 1-(4-Fluorobenzyl)piperazine dihydrochloride

Chemical Property:

PSA：15.27000
LogP:3.10160
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:266.0752821
Heavy Atom Count:16
Complexity:161

Purity/Quality:

99% ^*data from raw suppliers

4-fluoro BZP (hydrochloride) ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)CC2=CC=C(C=C2)F.Cl.Cl
Description Benzylpiperazines (BZP) are stimulant drugs which inhibit monoamine uptake. BZP and substituted derivatives, such as 1-(3,4-methylenedioxybenzyl)piperazine, have been identified as designer drugs or drugs of abuse. 4-fluoro BZP is a substituted BZP with a potential for abuse. The physiological and toxicological properties of 1-(4-FLUORO-BENZYL)-PIPERAZINE 2HCL have not been evaluated. This product is intended for forensic and research applications. 4-fluoro BZP is also used as a precursor in the synthesis of certain bioactive compounds.

Technology Process of 1-(4-Fluorobenzyl)piperazine dihydrochloride

There total 5 articles about 1-(4-Fluorobenzyl)piperazine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 7542-23-6,8006-71-1
piperazine hydrochloride

: 352-11-4
1-chloromethyl-4-fluorobenzene

: 199672-06-5,449174-90-7
1-(4-fluorobenzyl)piperazine monohydrochloride

Guidance literature:: at 65 ℃; for 0.416667h;
DOI:10.1016/j.bmc.2005.04.012

Reference yield: 88.0%

: 142-64-3,8006-71-1
piperazine dihydrochloride

: 352-11-4
1-chloromethyl-4-fluorobenzene

: 199672-06-5,449174-90-7
1-(4-fluorobenzyl)piperazine monohydrochloride

Guidance literature:: piperazine dihydrochloride; In methanol; Heating;

1-chloromethyl-4-fluorobenzene; With copper(II) ions supported on commercial polymeric resin; at 20 ℃;
DOI:10.3390/molecules25092168