Prop-1-ene-2-thiol

Base Information

• Chemical Name: Prop-1-ene-2-thiol
• CAS No.: 2028-39-9
• Molecular Formula: C3H6S
• Molecular Weight: 74.1466
• DSSTox Substance ID: DTXSID90570666
• Nikkaji Number: J464.884F
• Wikidata: Q82458191
• Mol file: 2028-39-9.mol

Synonyms:2-mercaptopropene;Prop-1-ene-2-thiol;2028-39-9;DTXSID90570666

Chemical Property of Prop-1-ene-2-thiol

Chemical Property:

• XLogP3: 1.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 74.01902136
• Heavy Atom Count: 4
• Complexity: 30.3

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=C)S

Technology Process of Prop-1-ene-2-thiol

There total 1 articles about Prop-1-ene-2-thiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-2-thiol propionitrile (135986-79-7) → thioacetone (4756-05-2) + 2-mercaptopropene (2028-39-9)

Guidance literature:

With potassium carbonate; at 200 ℃; under 1E-06 Torr;

DOI:10.1016/S0040-4020(01)80958-3

Reference yield: 71.0%

2-mercaptopropene (2028-39-9) + mesitylenecarbonitrile oxide (2904-57-6) → 2,4,6-Trimethylbenzthiohydroximsaeure-S-(1-methylvinyl)ester (113475-88-0)

Guidance literature:

With lithium diisopropyl amide;

Reference yield:

[1S-[1α,2β,3β,4α(1S*,2R*)]]-N-ethyl-2,3-dihydroxy-4-[7-(2-phenylcyclopropylamino)-5-(propylsulfonyl)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-cyclopentanecarboxamide + 2-mercaptopropene (2028-39-9) → [1S-[1α,2β,3β,4α(1S*,2R*)]]-N-ethyl-2,3-dihydroxy-4-[7-[(2-phenylcyclopropyl)amino]-5-(2-propenylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-cyclopentanecarboxamide

Guidance literature:

upstream raw materials:

2-methyl-2-thiol propionitrile

Downstream raw materials:

2,4,6-Trimethylbenzthiohydroximsaeure-S-(1-methylvinyl)ester