2-(2-PYRIDIN-2-YLETHYL)MALONIC ACID

Base Information

Chemical Name:2-(2-PYRIDIN-2-YLETHYL)MALONIC ACID
CAS No.:203247-83-0
Molecular Formula:C₁₀H₁₁NO₄
Molecular Weight:209.202
Hs Code.:
Mol file:203247-83-0.mol

Synonyms:(2-[2]Pyridyl-aethyl)-[2]thienylmethyl-amin;2-(pyridin-2-yl)-n-(thiophen-2-ylmethyl)ethanamine;(2-[2]Pyridyl-aethyl)-malonsaeure;(2-[2]pyridyl-ethyl)-malonic acid;(2-[2]pyridyl-ethyl)-[2]thienylmethyl-amine;diester of 2-(pyridylethyl)malonic acid;

Suppliers and Price of 2-(2-PYRIDIN-2-YLETHYL)MALONIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 7 raw suppliers

Chemical Property of 2-(2-PYRIDIN-2-YLETHYL)MALONIC ACID

Chemical Property:

Melting Point:138 °C (decomp)
Boiling Point:409.3±35.0 °C(Predicted)
PKA:2.60±0.34(Predicted)
PSA：87.49000
Density:1.352±0.06 g/cm3(Predicted)
LogP:0.79960

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(2-PYRIDIN-2-YLETHYL)MALONIC ACID

There total 4 articles about 2-(2-PYRIDIN-2-YLETHYL)MALONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 84199-92-8
diethyl 2-(2-pyridyl)ethylmalonate

: 203247-83-0
(2-[2]pyridyl-ethyl)-malonic acid

Guidance literature:: With sodium hydroxide;
DOI:10.1021/ja01202a063

Reference yield:

: 16927-00-7
2-(2-chloroethyl)pyridine

: 203247-83-0
(2-[2]pyridyl-ethyl)-malonic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaH; KI / dimethylformamide / 0.5 h / cooling

1.2: dimethylformamide / 48 h / 80 °C

2.1: aq. KOH / ethanol / 3 h / Heating

With potassium hydroxide; sodium hydride; potassium iodide; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm0309147

Reference yield:

: 100-69-6,25014-15-7,27476-03-5,329041-71-6
2-vinylpyridine

: 203247-83-0
(2-[2]pyridyl-ethyl)-malonic acid

Guidance literature:: Multi-step reaction with 2 steps

1: sodium

2: aqueous NaOH

With sodium hydroxide; sodium;
DOI:10.1021/ja01202a063