Diethyl [2-(pyridin-2-yl)ethyl]propanedioate

Base Information

Chemical Name:Diethyl [2-(pyridin-2-yl)ethyl]propanedioate
CAS No.:84199-92-8
Molecular Formula:C14H19NO4
Molecular Weight:265.30500
Hs Code.:
DSSTox Substance ID:DTXSID80575342
Wikidata:Q82464673
Mol file:84199-92-8.mol

Synonyms:84199-92-8;Diethyl [2-(pyridin-2-yl)ethyl]propanedioate;diethyl 2-(2-pyridin-2-ylethyl)propanedioate;diethyl 2-(2-(pyridin-2-yl)ethyl)malonate;Propanedioic acid, [2-(2-pyridinyl)ethyl]-, diethyl ester;AKOS017547885;SCHEMBL7810585;AMY2410;diethyl beta-pyridyl-ethylmalonate;DTXSID80575342;XVPMESFRZJJXGY-UHFFFAOYSA-N;Diethyl beta-(2-pyridyl)-ethylmalonate;DIETHYL 2-[2-(2-PYRIDINYL)ETHYL]MALONATE;1,3-DIETHYL 2-[2-(PYRIDIN-2-YL)ETHYL]PROPANEDIOATE

Suppliers and Price of Diethyl [2-(pyridin-2-yl)ethyl]propanedioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 8 raw suppliers

Chemical Property of Diethyl [2-(pyridin-2-yl)ethyl]propanedioate

Chemical Property:

PSA：65.49000
LogP:1.75660
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:265.13140809
Heavy Atom Count:19
Complexity:275

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(CCC1=CC=CC=N1)C(=O)OCC

Technology Process of Diethyl [2-(pyridin-2-yl)ethyl]propanedioate

There total 5 articles about Diethyl [2-(pyridin-2-yl)ethyl]propanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 100-69-6,25014-15-7,27476-03-5,329041-71-6
2-vinylpyridine

: 105-53-3
diethyl malonate

: 84199-92-8
diethyl 2-(2-pyridyl)ethylmalonate

Guidance literature:: With sodium ethanolate; In ethanol;
DOI:10.1002/hlca.19820650621

Reference yield: 74.0%

: 2-Pyridin-2-yl-cyclopropane-1,1-dicarboxylic acid diethyl ester

: 84199-92-8
diethyl 2-(2-pyridyl)ethylmalonate

Guidance literature:: With N,N,N,N,N,N-hexamethylphosphoric triamide; samarium diiodide; In tetrahydrofuran; tert-butyl alcohol; for 0.166667h; Ambient temperature;
DOI:10.1248/cpb.43.2075

Reference yield:

: 16927-00-7
2-(2-chloroethyl)pyridine

: 105-53-3
diethyl malonate

: 84199-92-8
diethyl 2-(2-pyridyl)ethylmalonate

Guidance literature:: diethyl malonate; With sodium hydride; potassium iodide; In N,N-dimethyl-formamide; for 0.5h; cooling;

2-(2-chloroethyl)pyridine; In N,N-dimethyl-formamide; at 80 ℃; for 48h;
DOI:10.1021/jm0309147