1-BROMONAPHTHALENE-5-ACETIC ACID METHYL ESTER

Base Information

• Chemical Name: 1-BROMONAPHTHALENE-5-ACETIC ACID METHYL ESTER
• CAS No.: 20366-57-8
• Molecular Formula: C11H9BrO
• Molecular Weight: 237.096
• Mol file: 20366-57-8.mol

Synonyms:5-Bromo-1-naphthalenemethanol;(5-Brom-naphthyl-(1))-carbinol;5-bromo-1-hydroxymethylnaphthalene;(5-Brom-[1]naphthyl)-methanol;(5-bromo-[1]naphthyl)-methanol;(5-bromonaphthalen-1-yl)methanol;

Chemical Property of 1-BROMONAPHTHALENE-5-ACETIC ACID METHYL ESTER

Chemical Property:

• PSA: 20.23000
• LogP: 3.09460

Purity/Quality:

99%min. ^*data from raw suppliers

5-Bromonaphthalene-1-methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-BROMONAPHTHALENE-5-ACETIC ACID METHYL ESTER

There total 5 articles about 1-BROMONAPHTHALENE-5-ACETIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

5-bromo-1-naphthaldehyde (41498-06-0) → (5-bromo-naphthalen-1-yl)-methanol (20366-57-8)

Guidance literature:

5-bromo-1-naphthaldehyde; With sodium tetrahydroborate; In ethanol; at 20 ℃; for 0.5h;

With water; In dichloromethane;

Reference yield:

5-bromo-1-naphthalenecarboxylic acid (16726-67-3) → (5-bromo-naphthalen-1-yl)-methanol (20366-57-8)

Guidance literature:

Multistep reaction; (i) MeOH, H₂SO₄, (ii) LiAlH₄, Et₂O;

Reference yield:

5-bromo-1-naphthoic acid methyl ester (59866-97-6) → (5-bromo-naphthalen-1-yl)-methanol (20366-57-8)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1021/ja00877a024

upstream raw materials:

5-bromo-1-naphthaldehyde

5-bromo-1-naphthalenecarboxylic acid

5-bromo-1-naphthoic acid methyl ester

ethanol

Downstream raw materials:

5-bromo-1-naphthaldehyde

C₁₉H₁₆F₃NO

(5-(2-methyl-4-(trifluoromethyl)phenyl)naphthalen-1-yl)methanol

(5-(2-methoxy-4-(trifluoromethyl)phenyl)naphthalen-1-yl)methanol