Piperidine, 2,2,6,6-tetramethyl-1-[(3-phenyl-2-propenyl)oxy]-

Base Information

• Chemical Name: Piperidine, 2,2,6,6-tetramethyl-1-[(3-phenyl-2-propenyl)oxy]-
• CAS No.: 204906-02-5
• Molecular Formula: C18H27NO
• Molecular Weight: 273.418
• Mol file: 204906-02-5.mol

Synonyms:

Chemical Property of Piperidine, 2,2,6,6-tetramethyl-1-[(3-phenyl-2-propenyl)oxy]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Piperidine, 2,2,6,6-tetramethyl-1-[(3-phenyl-2-propenyl)oxy]-

There total 9 articles about Piperidine, 2,2,6,6-tetramethyl-1-[(3-phenyl-2-propenyl)oxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

allylbenzene (300-57-2,57807-91-7) + 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical (2564-83-2,45842-10-2,126517-51-9,25657-03-8,26933-82-4,54637-06-8,64104-42-3) → 1-(cinnamyloxy)-2,2,6,6-tetramethylpiperidine (204906-02-5)

Guidance literature:

With tert.-butylhydroperoxide; tetra-(n-butyl)ammonium iodide; In decane; benzene; at 20 - 90 ℃; for 12h; Schlenk technique;

DOI:10.1055/s-0034-1379142

Reference yield: 45.0%

2,2,6,6-tetramethyl-piperidine-N-oxyl (2564-83-2) + (η3-PhCHCHCH2)bis(triphenylphosphine)palladium tetrafluoroborate → 1-(cinnamyloxy)-2,2,6,6-tetramethylpiperidine (204906-02-5)

Guidance literature:

With Ir(ppy)₂(dtbbpy)PF₆; caesium carbonate; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃; for 12h; Inert atmosphere; Glovebox; Sealed tube; Irradiation;

DOI:10.1021/jacs.1c06271

Reference yield: 18.0%

2,2,6,6-Tetramethyl-1-piperidinyloxy free radical (2564-83-2,45842-10-2,126517-51-9,25657-03-8,26933-82-4,54637-06-8,64104-42-3) + diethyl 3-phenylprop-2-enyl phosphate → 1-(cinnamyloxy)-2,2,6,6-tetramethylpiperidine (204906-02-5)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; 2-phenyl-1,2,3,4-tetrahydroisoquinoline; (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; In acetonitrile; at 20 ℃; for 48h; Schlenk technique; Inert atmosphere; Irradiation;

DOI:10.1002/anie.201409999

upstream raw materials:

allylbenzene

2,2,6,6-Tetramethyl-1-piperidinyloxy free radical

3-bromo-1-phenyl-1-propenyl bromide

1-phenyl-3-iodopropene