N-[3-(2-bromoacetyl)phenyl]methanesulfonamide

Base Information

• Chemical Name: N-[3-(2-bromoacetyl)phenyl]methanesulfonamide
• CAS No.: 2065-04-5
• Molecular Formula: C9H10BrNO3S
• Molecular Weight: 292.153
• European Community (EC) Number: 868-538-6
• Mol file: 2065-04-5.mol

Synonyms:2065-04-5;N-[3-(2-bromoacetyl)phenyl]methanesulfonamide;N-(3-(2-Bromoacetyl)phenyl)methanesulfonamide;2-bromo-1-[3-[(methylsulfonyl)amino]phenyl]ethanone;starbld0044777;Methanesulfonamide, N-[3-(bromoacetyl)phenyl]-;SCHEMBL1120803;CPSLFLKTEZYTER-UHFFFAOYSA-N;AKOS000278455;3'-(2-bromoacetyl)methanesulfonanilide;CS-0116993;EN300-9493480;2-bromo-1-[3-(methylsulfonyl)aminophenyl]ethanone;N-[3-(2-Bromo-acetyl)-phenyl]-methanesulfonamide

Chemical Property of N-[3-(2-bromoacetyl)phenyl]methanesulfonamide

Chemical Property:

• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 290.95648
• Heavy Atom Count: 15
• Complexity: 323

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CS(=O)(=O)NC1=CC=CC(=C1)C(=O)CBr

Technology Process of N-[3-(2-bromoacetyl)phenyl]methanesulfonamide

There total 4 articles about N-[3-(2-bromoacetyl)phenyl]methanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-[3-[N-(methylsulfonyl)amino]phenyl]ethanone (2417-42-7) → 2-bromo-1-[3-[(methylsulfonyl)amino]phenyl]ethanone (2065-04-5)

Guidance literature:

With bromine; dibenzoyl peroxide; In diethyl ether;

DOI:10.1021/jm00319a023

Reference yield:

1-(3-aminophenyl)ethanone (99-03-6) + benzenesulfonyl chloride (1939-99-7) → 1-[3-benzylsulfonylamino)phenyl]ethanone + 2-bromo-1-[3-[(methylsulfonyl)amino]phenyl]ethanone (2065-04-5)

Guidance literature:

With pyridine;

Reference yield:

1-(3-aminophenyl)ethanone (99-03-6) → 2-bromo-1-[3-[(methylsulfonyl)amino]phenyl]ethanone (2065-04-5)

Guidance literature:

Multi-step reaction with 2 steps

1: Py

2: Br₂, (PhCO)2O₂ / diethyl ether

With pyridine; bromine; dibenzoyl peroxide; In diethyl ether;

DOI:10.1021/jm00319a023

upstream raw materials:

1-[3-[N-(methylsulfonyl)amino]phenyl]ethanone

1-(3-aminophenyl)ethanone

benzenesulfonyl chloride

Downstream raw materials:

N-(3-Benzo[d]imidazo[2,1-b]thiazol-2-yl-phenyl)-methanesulfonamide

N-(3-(6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)phenyl)methanesulfonamide

(+/-)-N-[5-(2-bromo-1-hydroxyethyl)-2-benzyloxyphenyl]-N,N-dimethylsulfamide

N-[3-(2-Amino-1-hydroxy-ethyl)-phenyl]-methanesulfonamide