2,3,4-Triphenyl-1,2,4-oxadiazolidin-5-one

Base Information

• Chemical Name: 2,3,4-Triphenyl-1,2,4-oxadiazolidin-5-one
• CAS No.: 21978-65-4
• Molecular Formula: C20H16 N2 O2
• Molecular Weight: 316.359
• NSC Number: 102889
• Mol file: 21978-65-4.mol

Synonyms:2,3,4-Triphenyl-1,2,4-oxadiazolidin-5-one;21978-65-4;NSC102889;NSC 102889;SCHEMBL3868478;STL239433;AKOS000478391;AKOS025278227;NSC-102889

Chemical Property of 2,3,4-Triphenyl-1,2,4-oxadiazolidin-5-one

Chemical Property:

• Vapor Pressure: 5.2E-08mmHg at 25°C
• Boiling Point: 442°Cat760mmHg
• Flash Point: 221.1°C
• Density: 1.26g/cm³
• XLogP3: 5.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 316.121177757
• Heavy Atom Count: 24
• Complexity: 423

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2N(C(=O)ON2C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 2,3,4-Triphenyl-1,2,4-oxadiazolidin-5-one

There total 2 articles about 2,3,4-Triphenyl-1,2,4-oxadiazolidin-5-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

phenyl isocyanate (1197040-29-1,931-54-4) + N-(benzylidene)aniline N-oxide (1137-96-8,26505-49-7,201024-81-9) → 2,3,4-triphenyl-1,2,4-oxadiazolidin-5-one (21978-65-4)

Guidance literature:

With silver(l) oxide; In 1,4-dioxane; at 80 ℃; for 4h; Schlenk technique;

DOI:10.1021/acs.joc.9b03279

Reference yield:

phenyl isocyanate (103-71-9) + C,N-diphenylnitrone (201024-81-9) → 2,3,4-triphenyl-1,2,4-oxadiazolidin-5-one (21978-65-4)

Guidance literature:

Reference yield:

2,3,4-triphenyl-1,2,4-oxadiazolidin-5-one (21978-65-4) → N,N'-diphenylbenzamidine (2556-46-9,141417-98-3)

Guidance literature:

With potassium hydroxide; In methanol; for 48h; Ambient temperature;

upstream raw materials:

phenyl isocyanate

C,N-diphenylnitrone

phenyl isocyanate

N-(benzylidene)aniline N-oxide

Downstream raw materials:

N,N'-diphenylbenzamidine