Isoxazole, 4,5-dihydro-5-(4-methylphenyl)-3-phenyl-

Base Information

Chemical Name:Isoxazole, 4,5-dihydro-5-(4-methylphenyl)-3-phenyl-
CAS No.:20821-95-8
Molecular Formula:C16H15NO
Molecular Weight:237.301
Hs Code.:
DSSTox Substance ID:DTXSID80443138
Nikkaji Number:J933.046A

Synonyms:20821-95-8;Isoxazole, 4,5-dihydro-5-(4-methylphenyl)-3-phenyl-;3-phenyl-5-(p-tolyl)-4,5-dihydroisoxazole;DTXSID80443138;3-Phenyl-5-(4-methylphenyl)-2-isoxazoline

Suppliers and Price of Isoxazole, 4,5-dihydro-5-(4-methylphenyl)-3-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Isoxazole, 4,5-dihydro-5-(4-methylphenyl)-3-phenyl-

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:237.115364102
Heavy Atom Count:18
Complexity:298

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2CC(=NO2)C3=CC=CC=C3

Technology Process of Isoxazole, 4,5-dihydro-5-(4-methylphenyl)-3-phenyl-

There total 26 articles about Isoxazole, 4,5-dihydro-5-(4-methylphenyl)-3-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 3-phenyl-5-(p-methylphenyl)-2-N-(p-methoxybenzyl)isoxazolidine

: 20821-95-8
5-(4-methylphenyl)-3-phenyl-4,5-dihydroisoxazole

Guidance literature:: With triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; water; for 2h; Ambient temperature;
DOI:10.1021/jo971021n

Reference yield: 86.0%

: 622-97-9,24936-41-2
1-ethenyl-4-methylbenzene

: 932-90-1
Benzaldoxime

: 20821-95-8
5-(4-methylphenyl)-3-phenyl-4,5-dihydroisoxazole

Guidance literature:: With Oxone; potassium iodide; In methanol; water; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1039/c3cc41164h

Reference yield: 84.0%

: 1-phenyl-3-p-tolyl-propan-1-one oxime

: 16112-19-9
5-(p-methylphenyl)-3-phenyl-2-isoxazole

: 20821-95-8
5-(4-methylphenyl)-3-phenyl-4,5-dihydroisoxazole

Guidance literature:: With Oxone; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium iodide; In acetonitrile; at 50 ℃; for 48h; Reagent/catalyst;
DOI:10.1002/asia.202100572