1,2,3-Trimethoxy-5-[2-(4-methoxyphenyl)ethynyl]benzene

Base Information

Chemical Name:1,2,3-Trimethoxy-5-[2-(4-methoxyphenyl)ethynyl]benzene
CAS No.:208347-68-6
Molecular Formula:C18H18O4
Molecular Weight:298.339
Hs Code.:
DSSTox Substance ID:DTXSID70433907
Nikkaji Number:J2.336.620G
Wikidata:Q82248180

Synonyms:208347-68-6;1,2,3-trimethoxy-5-[2-(4-methoxyphenyl)ethynyl]benzene;Benzene, 1,2,3-trimethoxy-5-[(4-methoxyphenyl)ethynyl]-;Benzene, 1,2,3-trimethoxy-5-[2-(4-methoxyphenyl)ethynyl]-;SCHEMBL18130094;DTXSID70433907;XVYOJBGBNUPSIP-UHFFFAOYSA-N;STL433316;AKOS016347735;1,2,3-Trimethoxy-5-(4-methoxyphenylethynyl)benzene;1,2,3-trimethoxy-5-[(4-methoxyphenyl)ethynyl]benzene;1,2,3-TRIMETHOXY-5-[2-(4-METHOXYPHENYL)-1-ETHYNYL]BENZENE

Suppliers and Price of 1,2,3-Trimethoxy-5-[2-(4-methoxyphenyl)ethynyl]benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 1,2,3-Trimethoxy-5-[2-(4-methoxyphenyl)ethynyl]benzene

Chemical Property:

PSA：36.92000
LogP:3.12080
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:298.12050905
Heavy Atom Count:22
Complexity:374

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C#CC2=CC(=C(C(=C2)OC)OC)OC

Technology Process of 1,2,3-Trimethoxy-5-[2-(4-methoxyphenyl)ethynyl]benzene

There total 5 articles about 1,2,3-Trimethoxy-5-[2-(4-methoxyphenyl)ethynyl]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 53560-33-1
3,4,5-trimethoxyphenylacetylene

: 696-62-8
para-iodoanisole

: 208347-68-6
1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)acetylene

Guidance literature:: With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; diethylamine; at 20 - 50 ℃; Inert atmosphere;
DOI:10.1016/j.bmc.2013.12.015

Reference yield: 57.0%

: 33675-41-1
1-bromo-2-(4-methoxyphenyl)acetylene

: 208347-68-6
1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)acetylene

Guidance literature:: 1-bromo-2-(4-methoxyphenyl)acetylene; With iron(III)-acetylacetonate; In tetrahydrofuran; at 20 ℃; for 0.166667h; Inert atmosphere;

3,4,5-(MeO)C₆H₂(CuCl)MgBr; In tetrahydrofuran; at 25 ℃; Inert atmosphere;
DOI:10.1002/ejoc.201000393

Reference yield: 57.0%

: 33675-41-1
1-bromo-2-(4-methoxyphenyl)acetylene

: 133095-91-7
3,4,5-trimethoxyphenylmagnesium bromide

: 208347-68-6
1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)acetylene

Guidance literature:: 3,4,5-trimethoxyphenylmagnesium bromide; With copper(l) chloride; In tetrahydrofuran; at 25 ℃; for 0.333333h;

1-bromo-2-(4-methoxyphenyl)acetylene; With iron(III)-acetylacetonate; at 20 ℃;
DOI:10.1002/ejoc.201000924